Volume 21, Number 6—June 2015
Dispatch
Drug Resistance–Associated Mutations in Mycoplasma genitalium in Female Sex Workers, Japan
Takashi Deguchi
, Mitsuru Yasuda, Kengo Horie, Kensaku Seike, Mina Kikuchi, Kohsuke Mizutani, Tomohiro Tsuchiya, Shigeaki Yokoi, Masahiro Nakano, and Shinji Hoshina
, Mitsuru Yasuda, Kengo Horie, Kensaku Seike, Mina Kikuchi, Kohsuke Mizutani, Tomohiro Tsuchiya, Shigeaki Yokoi, Masahiro Nakano, and Shinji Hoshina
Table 2
Mutations in the 23S rRNA gene and amino acid changes in GyrA and ParC in Mycoplasma genitalium detected in female sex workers, Japan*
| Female sex worker | Specimen type | Mutations in the 23S rRNA gene | Amino acid changes in |
|
|---|---|---|---|---|
| GyrA | ParC | |||
| 1 | Vaginal swab | A-2058→G | – | – |
| 2 | Vaginal swab | NA | – | – |
| 3 | Vaginal swab | – | – | – |
| 4 | Vaginal swab | – | – | – |
| 5 | Vaginal swab | A-2058→G | – | – |
| 6 | Vaginal swab | A-2059→G | – | Ser-80→Ile |
| 7 | Vaginal swab | NA | – | NA |
| 8 | Vaginal swab | – | – | – |
| 9 | Vaginal swab | – | – | – |
| 10 | Vaginal swab | – | – | – |
| 11 | Throat washing | NA | NA | NA |
| 12 | Vaginal swab | – | – | – |
| 13 | Vaginal swab | NA | – | – |
| 14 | Vaginal swab | A-2059→G | – | Ser-80→Ile |
| 15 | Vaginal swab | A-2058→G | – | Ser-80→Asn |
| 16 | Vaginal swab | NA | – | Ser-80→Ile |
| 17 | Vaginal swab | – | – | Ser-80→Ile |
| 18 | Vaginal swab | – | – | – |
| 19 | Vaginal swab | – | – | Ser-80→Asn |
| 20 | Vaginal swab | A-2058→G | – | Ser-80→Asn |
| 21 | Vaginal swab | A-2058→G | – | – |
| 22 | Vaginal swab | A-2058→G | – | NA |
*The nucleotide positions in the 23S rRNA gene and the amino acid positions in ParC are numbered according to Escherichia coli numbering. –, no mutations in the 23S rRNA gene nor amino acid changes in GyrA or ParC were found in the analyzed regions; NA, specimens could not be analyzed for the 23S rRNA, gyrA, or parC genes.
Page created: May 15, 2015
Page updated: May 15, 2015
Page reviewed: May 15, 2015
The conclusions, findings, and opinions expressed by authors contributing to this journal do not necessarily reflect the official position of the U.S. Department of Health and Human Services, the Public Health Service, the Centers for Disease Control and Prevention, or the authors' affiliated institutions. Use of trade names is for identification only and does not imply endorsement by any of the groups named above.