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Volume 21, Number 7—July 2015
Research

Seroprevalence for Hepatitis E and Other Viral Hepatitides among Diverse Populations, Malawi

Taha E. TahaComments to Author , Laura K. Rusie, Alain Labrique, Mulinda Nyirenda, Dean Soko, Melvin Kamanga, Johnstone Kumwenda, Homayoon Farazadegan, Kenrad Nelson, and Newton Kumwenda
Author affiliations: Johns Hopkins University, Baltimore, Maryland, USA (T.E. Taha, L.K. Rusie, A. Labrique, H. Farazadegan, K. Nelson, N. Kumwenda); Queen Elizabeth Central Hospital, Blantyre, Malawi (M. Nyirenda); Johns Hopkins Research Project, Blantyre (D. Soko, M. Kamanga); University of Malawi, Blantyre (J. Kumwenda)

Main Article

Table 3

Crude and adjusted odds ratios for enterically transmitted hepatitis E virus, Malawi*

Characteristics Crude OR p value Adjusted OR (95% CI)
Study, period
ICAR, 1989–1995 Reference NA Reference
SUCOMA, 1994–1999 2.80 0.03 3.54 (0.75–16.76)
NVAZ, 2000–2003 1.39 0.51 1.59 (0.55–4.62)
MWANZA, 2001 1.59 0.37 1.85 (0.51–6.70)
METRO, 2003–2005 3.82 0.004 3.44 (1.37–8.67)
PEPI, 2004–2009
1.59
0.35
1.87 (0.64–5.49)
Enrollment year†
1.02
0.38
NA
HIV status
HIV-negative Reference NA Reference
HIV-positive
0.59
0.01
0.72 (0.38–1.36)
Age, y†
1.01
0.56
1.00 (0.97–1.02)
Age range, y
15–19 Reference NA NA
20–29 0.81 0.51 NA
30–39 0.71 0.33 NA
40–49 0.55 0.22 NA
50–59 2.07 0.21 NA
60–69
4.13
0.17
NA
Sex
M Reference NA 1.00
F
0.83
0.36
1.40 (0.41–4.76)
Setting
Rural Reference NA NA
Urban
0.85
0.41
NA
Running water in house
No Reference NA 1.00
Yes
0.61
0.06
1.40 (0.41–4.76)
Electricity in house
No Reference NA NA
Yes
0.82
0.40
NA
Education
None Reference NA NA
Any
0.92
0.78
NA
Marital status
Married Reference NA NA
Single
0.60
0.14
NA
Employment status
Unemployed Reference NA NA
Employed
1.18
0.41
NA
Parity† 0.90 0.61 NA

*OR, odds ratio; ICAR, International Collaborations on AIDS Research; SUCOMA, a study of HIV prevalence among male workers for the Sugar Company of Malawi; NVAZ, a study of efficacy of nevirapine/zidovudinel post-exposure prophylaxis to prevent mother-to-child transmission of HIV; MWANZA, a study of risk factors associated with prevalent HIV infection in the rural town of Malawi; METRO, a study in which efficacy of intravaginal metronidazole gel in reducing bacterial vaginosis was assessed; PEPI, a study of antiretroviral postexposure prophylaxis to prevent mother-to-child transmission of HIV; NA: not applicable.
†Continuous variable.

Main Article

Page created: June 12, 2015
Page updated: June 12, 2015
Page reviewed: June 12, 2015
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