Volume 21, Number 8—August 2015
Synopsis
Real-Time Microbiology Laboratory Surveillance System to Detect Abnormal Events and Emerging Infections, Marseille, France
Cédric Abat, Hervé Chaudet, Philippe Colson, Jean-Marc Rolain, and Didier Raoult
Table 2
Summary of the normal phenotypes registered in MARSS*
| Bacterial species |
Resistance phenotypes |
β-lactam antibiotics |
||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AMX |
TIC |
AMC |
TCC |
TZP |
FOX |
OXA |
CRO |
FEP |
CAZ |
IPM |
||
| Escherichia coli | ||||||||||||
| Wild-type | S | S | S | S | S | S | S | |||||
| Low-level penicillinase | I/R | I/R | S | S | S | S | S | |||||
| Inhibitor-resistant penicillinase | I/R | I/R | R | R | S | S | S | |||||
| High-level penicillinase | I/R | I/R | I/R | I/R | S | S | S | |||||
| ESBL | R | R | S/I/R | S/I/R | I/R | I/R | S | |||||
| High-level cephalosporinase |
R |
R |
R |
R |
R |
S |
S |
|||||
| Klebsiella pneumoniae | Wild-type | S | S | S | S | S | ||||||
| ESBL | I/R | I/R | I/R | I/R | S | |||||||
| High-level cephalosporinase | I/R | I/R | I/R | S | S | |||||||
| ESBL-TZP-sensible |
I/R |
S |
I/R |
I/R |
S |
|||||||
| Proteus mirabilis |
Wild | S | S | S | S | S | S | S | ||||
| Low-level penicillinase | I/R | I/R | S | S | S | S | S | |||||
| Inhibitor-resistant penicillinase | R | R | R | R | S | S | S | |||||
| High-level penicillinase | R | R | I/R | I/R | S | S | S | |||||
| ESBL | R | R | I/R | I/R | I/R | I/R | S | |||||
| High-level cephalosporinase |
R |
R |
R |
R |
R |
S |
S |
|||||
| Klebsiella oxytoca |
Wild-type | S | S | S | S | |||||||
| ESBL | I/R | I/R | I/R | S | ||||||||
| High-level penicillinase | I/R | S/I/R | S | S | ||||||||
| Low-level penicillinase | S | R | S | S | ||||||||
| ESBL–TZP-sensible |
I/R |
S |
I/R |
S |
||||||||
| Enterobacter aerogenes |
Wild-type | S | S | S | S | S | ||||||
| Inhibitors-resistant penicillinase | R | R | S | S | S | |||||||
| ESBL | S/I/R | I/R | I/R | I/R | S | |||||||
| High-level cephalosporinase |
I/R |
I/R |
I/R |
S |
S |
|||||||
| Morganella morganii |
Wild-type | S | S | S | S | S | ||||||
| Inhibitor-resistant penicillinase | R | R | S | S | S | |||||||
| ESBL | S/I/R | I/R | I/R | I/R | S | |||||||
| High-level cephalosporinase |
I/R |
I/R |
I/R |
S |
S |
|||||||
| Serratia marcescens |
Wild-type | S | S | S | S | S | ||||||
| Inhibitor-resistant penicillinase | R | R | S | S | S | |||||||
| ESBL | S/I/R | I/R | I/R | I/R | S | |||||||
| High-level cephalosporinase |
I/R |
I/R |
I/R |
S |
S |
|||||||
| Enterobacter cloacae |
Wild-type | S | S | S | S | S | ||||||
| Inhibitor-resistant penicillinase | R | R | S | S | S | |||||||
| ESBL | S/I/R | I/R | I/R | I/R | S | |||||||
| High-level cephalosporinase |
I/R |
I/R |
I/R |
S |
S |
|||||||
| Pseudomonas aeruginosa |
Wild-type | S | S | S | S | S | S | |||||
| Penicillinase | R | R/I/S | I/S | S | S | S | ||||||
| High-level penicillinase | I/R | I/R | I/R | S | S | S | ||||||
| ESBL | I/R | I/R | I/R | I/R | I/R | S | ||||||
| Selective permeability to imipenem | S | S | S | S | S | R | ||||||
| Penicillinase, loss of D2 porine |
R |
R |
S |
S |
S |
R |
||||||
| Acinetobacter baumannii |
Wild-type | S | S | S | S | |||||||
| Penicillinase | R | R/I/S | S | S | ||||||||
| ESBL |
I/R |
I/R |
I/R |
S |
||||||||
| Streptococcus agalactiae |
Wild | S | S | |||||||||
| Oxacillin-resistant |
I/R |
S |
||||||||||
| Enterococcus faecalis |
Wild-type |
S |
||||||||||
| E. faecium |
Wild-type |
I/R |
||||||||||
| Staphylococcus aureus |
Wild-type | S | ||||||||||
| Methicillin-resistant |
I/R |
|||||||||||
| S. epidermidis | Wild-type | S | ||||||||||
| Methicillin-resistant | I/R | |||||||||||
*MARSS, Marseille Antibiotic Resistance Surveillance System; AMC, amoxicillin; TIC, ticarcillin; AMC, amoxicillin/clavulanic acid; TIC, ticarcillin/clavulanic acid; TZP, piperacillin/tazobactam; FOX, cefoxitin; OXA, oxacillin; CRO, ceftriaxone; FEP, cefepime; CAZ, ceftazidime; IMP, imipenem; S, susceptible; I, intermediate; R, resistant; ESBL, extended-spectrum β-lactamase.
Page created: July 14, 2015
Page updated: July 14, 2015
Page reviewed: July 14, 2015
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