Skip directly to site content Skip directly to page options Skip directly to A-Z link Skip directly to A-Z link Skip directly to A-Z link
Volume 21, Number 8—August 2015
Research

Prevalence of Hepatitis E Virus Infection in Pigs at the Time of Slaughter, United Kingdom, 2013

Sylvia Grierson, Judith Heaney, Tanya Cheney, Dilys Morgan, Stephen Wyllie, Laura Powell, Donald Smith, Samreen Ijaz, Falko Steinbach, Bhudipa Choudhury, and Richard S. TedderComments to Author 
Author affiliations: Animal and Plant Health Agency, Addlestone, United Kingdom (S. Grierson, T. Cheney, S. Wyllie, L. Powell, F. Steinbach, B. Choudhury); Public Health England, London, United Kingdom (J. Heaney, D. Morgan, S. Ijaz, R.S. Tedder); University of Edinburgh, Edinburgh, Scotland, United Kingdom (D. Smith); University of Surrey, Guildford, United Kingdom (F. Steinbach); University College London, London (R. S. Tedder)

Main Article

Figure

Phylogeny of genotype 3 hepatitis E viruses from pigs and patients with acute hepatitis in the United Kingdom. Nucleotide sequences of a 304-nt open reading frame 2 fragment (positions 5994–6297 of reference sequence M73218) from pigs at slaughter (black dots, n = 23) or from cases in persons with acute hepatitis E in England and Wales in 2013 (open circles, n = 190) were used to produce a neighbor-joining tree on the basis of maximum composite likelihood distances. Reference sequences were porc

Figure. Phylogeny of genotype 3 hepatitis E viruses (HEVs) from pigs and patients with acute hepatitis in the United Kingdom. Nucleotide sequences of a 304-nt open reading frame 2 fragment (positions 5994–6297 of reference sequence M73218) from pigs at slaughter (black dots, n = 23) or from cases in persons with acute hepatitis E in England and Wales in 2013 (open circles, n = 190) were used to produce a neighbor-joining tree on the basis of maximum composite likelihood distances. GenBank accession numbers for porcine HEV sequences from this study are KP293752–774. Reference sequences were porcine sequences from Europe and North America from GenBank (gray dots, n = 36) and single examples of previously assigned HEV genotypes and subtypes for which complete genome sequences were available: 1, M73218; 2, M74506; 4, AJ272108; 5, AB573435; 6, AB602441; 7, KJ496143; 3a, AF082843; 3b, AB291955; 3c, FJ705359; 3e, AB248521; 3f, EU723514; 3g, AF455784; 3h, AB290312; 3i, FJ998008; 3j, AY115488; and 3ra, GU937805. Bootstrap support (500 replicates) for all major nodes, including those for genotypes 1–7, was weak (40%–70%), reflecting the short genome region and the large number of sequences analyzed. Arrow indicates the group 1/2 node.

Main Article

Page created: July 14, 2015
Page updated: July 14, 2015
Page reviewed: July 14, 2015
The conclusions, findings, and opinions expressed by authors contributing to this journal do not necessarily reflect the official position of the U.S. Department of Health and Human Services, the Public Health Service, the Centers for Disease Control and Prevention, or the authors' affiliated institutions. Use of trade names is for identification only and does not imply endorsement by any of the groups named above.
file_external