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Volume 21, Number 9—September 2015
THEME ISSUE
Emerging Infections Program
Emerging Infections Program

The US Influenza Hospitalization Surveillance Network

Sandra ChavesComments to Author , Ruth Lynfield, Mary Lou Lindegren, Joseph Bresee, and Lyn Finelli
Author affiliations: Centers for Disease Control and Prevention, Atlanta, Georgia, USA (S.S. Chaves, J. Bresee, L. Finelli); Minnesota Department of Health, St. Paul, Minnesota, USA (R. Lynfield); Vanderbilt University School of Medicine, Nashville, Tennessee, USA (M.L. Lindegren)

Main Article

Figure 4

Percentages of children and adults hospitalized with laboratory-confirmed influenza virus infection who received influenza antiviral treatment, during 2009–10 (total hospitalized patients = 8,866) and 2010–11 (total hospitalized patients = 6,040), United States. Numbers above bars denote numbers of patients who received influenza antiviral treatment. p<0.01 for all age groups and categories except for the age group >65 years (18). Data from FluSurv-NET.

Figure 4. Percentages of children and adults hospitalized with laboratory-confirmed influenza virus infection who received influenza antiviral treatment, during 2009–10 (total hospitalized patients = 8,866) and 2010–11 (total hospitalized patients = 6,040), United States. Numbers above bars denote numbers of patients who received influenza antiviral treatment. p<0.01 for all age groups and categories except for the age group >65 years (18). Data from FluSurv-NET.

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References
  1. Molinari  NA, Ortega-Sanchez  IR, Messonnier  ML, Thompson  WW, Wortley  PM, Weintraub  E, The annual impact of seasonal influenza in the US: measuring disease burden and costs. Vaccine. 2007;25:508696. DOIPubMedGoogle Scholar
  2. Brundage  JF, Shanks  GD. Deaths from bacterial pneumonia during 1918–19 influenza pandemic. Emerg Infect Dis. 2008;14:11939. DOIPubMedGoogle Scholar
  3. Louria  DB, Blumenfeld  HL, Ellis  JT, Kilbourne  ED, Rogers  DE. Studies on influenza in the pandemic of 1957–1958. II. Pulmonary complications of influenza. J Clin Invest. 1959;38:21365. DOIPubMedGoogle Scholar
  4. Novel Swine-Origin Influenza  A. (H1N1) Virus Investigation Team; Dawood FS, Jain S, Finelli L, Shaw MW, Lindstrom S, Garten RJ, et al. Emergence of a novel swine-origin influenza A (H1N1) virus in humans. N Engl J Med. 2009;360:2605–15.
  5. Schrag  SJ, Shay  DK, Gershman  K, Thomas  A, Craig  AS, Schaffner  W, ; Emerging Infections Program Respiratory Diseases Activity. Multistate surveillance for laboratory-confirmed, influenza-associated hospitalizations in children: 2003–2004. Pediatr Infect Dis J. 2006;25:395400. DOIPubMedGoogle Scholar
  6. Centers for Disease Control and Prevention. Prevention and control of influenza: recommendations of the Advisory Committee on Immunization Practices. MMWR Morb Mortal Wkly Rep. 2003;52:134.
  7. Fiore  AE, Shay  DK, Broder  K, Iskander  JK, Uyeki  TM, Mootrey  G, Prevention and control of influenza: recommendations of the Advisory Committee on Immunization Practices (ACIP), 2008. MMWR Recomm Rep. 2008;57(RR-7):160 .PubMedGoogle Scholar
  8. Dao  CN, Kamimoto  L, Nowell  M, Reingold  A, Gershman  K, Meek  J, Adult hospitalizations for laboratory-positive influenza during the 2005–2006 through 2007–2008 seasons in the United States. J Infect Dis. 2010;202:8818. DOIPubMedGoogle Scholar
  9. Creanga  AA, Kamimoto  L, Newsome  K, D’Mello  T, Jamieson  DJ, Zotti  ME, Seasonal and 2009 pandemic influenza A(H1N1) virus infection during pregnancy: a population-based study of hospitalized cases. Am J Obstet Gynecol. 2011;204(Suppl 1):S3845. DOIPubMedGoogle Scholar
  10. Dee  DL, Bensyl  DM, Gindler  J, Truman  BI, Allen  BG, D’Mello  T, Racial and ethnic disparities in hospitalizations and deaths associated with 2009 pandemic influenza A (H1N1) virus infections in the United States. Ann Epidemiol. 2011;21:62330. DOIPubMedGoogle Scholar
  11. Morgan  OW, Bramley  A, Fowlkes  A, Freedman  DS, Taylor  TH, Gargiullo  P, Morbid obesity as a risk factor for hospitalization and death due to 2009 pandemic influenza A(H1N1) disease. PLoS ONE. 2010;5:e9694. DOIPubMedGoogle Scholar
  12. Cox  CM, D’Mello  T, Perez  A, Reingold  A, Gershman  K, Yousey-Hindes  K, Increase in rates of hospitalization due to laboratory-confirmed influenza among children and adults during the 2009–10 influenza pandemic. J Infect Dis. 2012;206:13508. DOIPubMedGoogle Scholar
  13. Thompson  WW, Shay  DK, Weintraub  E, Brammer  L, Bridges  CB, Cox  NJ, Influenza-associated hospitalizations in the United States. JAMA. 2004;292:133340. DOIPubMedGoogle Scholar
  14. Zhou  H, Thompson  WW, Viboud  CG, Ringholz  CM, Cheng  PY, Steiner  C, Hospitalizations associated with influenza and respiratory syncytial virus in the United States, 1993–2008. Clin Infect Dis. 2012;54:142736. DOIPubMedGoogle Scholar
  15. Kostova  D, Reed  C, Finelli  L, Cheng  PY, Gargiullo  PM, Shay  DK, Influenza illness and hospitalizations averted by influenza vaccination in the United States, 2005–2011. PLoS ONE. 2013;8:e66312. DOIPubMedGoogle Scholar
  16. Reed  C, Chaves  SS, Daily Kirley  P, Emerson  R, Aragon  D, Hancock  EB, Estimating influenza disease burden from population-based surveillance data in the United States. PLoS ONE. 2015;10:e0118369. DOIPubMedGoogle Scholar
  17. Doshi  S, Kamimoto  L, Finelli  L, Perez  A, Reingold  A, Gershman  K, Description of antiviral treatment among adults hospitalized with influenza before and during the 2009 pandemic: United States, 2005–2009. J Infect Dis. 2011;204:184856. DOIPubMedGoogle Scholar
  18. Garg  S, Chaves  SS, Pérez  A, D'Mello  T, Gershman  K, Meek  J, Reduced influenza antiviral treatment among children and adults hospitalized with laboratory-confirmed influenza infection in the year after the 2009 pandemic. Clin Infect Dis. 2012;55:e1821. DOIPubMedGoogle Scholar
  19. Thompson  MG, Sokolow  LZ, Almendares  O, Openo  K, Farley  MM, Meek  J, Effectiveness of nonadjuvanted monovalent influenza A(H1N1)pdm09 vaccines for preventing reverse transcription polymerase chain reaction–confirmed pandemic influenza hospitalizations: case-control study of children and adults at 10 US influenza surveillance network sites. Clin Infect Dis. 2013;57:158792. DOIPubMedGoogle Scholar
  20. Wise  ME, Viray  M, Sejvar  JJ, Lewis  P, Baughman  AL, Connor  W, Guillain-Barré syndrome during the 2009–2010 H1N1 influenza vaccination campaign: population-based surveillance among 45 million Americans. Am J Epidemiol. 2012;175:11109. DOIPubMedGoogle Scholar
  21. Tokars  JI, Lewis  P, DeStefano  F, Wise  M, Viray  M, Morgan  O, The risk of Guillain-Barré syndrome associated with influenza A (H1N1) 2009 monovalent vaccine and 2009–2010 seasonal influenza vaccines: results from self-controlled analyses. Pharmacoepidemiol Drug Saf. 2012;21:54652. DOIPubMedGoogle Scholar
  22. Fiore  AE, Uyeki  TM, Broder  K, Finelli  L, Euler  GL, Singleton  JA, Prevention and control of influenza with vaccines: recommendations of the Advisory Committee on Immunization Practices (ACIP), 2010. MMWR Recomm Rep. 2010;59(RR-8):162 .PubMedGoogle Scholar
  23. Prosser  LA, Bridges  CB, Uyeki  TM, Hinrichsen  VL, Meltzer  MI, Molinari  NA, Health benefits, risks, and cost-effectiveness of influenza vaccination of children. Emerg Infect Dis. 2006;12:154858. DOIPubMedGoogle Scholar
  24. Nichol  KL. The efficacy, effectiveness and cost-effectiveness of inactivated influenza virus vaccines. Vaccine. 2003;21:176975. DOIPubMedGoogle Scholar
  25. Centers for Disease Control and Prevention. Estimated influenza illnesses and hospitalizations averted by influenza vaccination—United States, 2012–13 influenza season. MMWR Morb Mortal Wkly Rep. 2013;62:9971000 .PubMedGoogle Scholar
  26. Dharan  NJ, Sokolow  LZ, Cheng  PY, Gargiullo  P, Gershman  K, Lynfield  R, Child, household, and caregiver characteristics associated with hospitalization for influenza among children 6–59 months of age: an Emerging Infections Program study. Pediatr Infect Dis J. 2014;33:e14150. DOIPubMedGoogle Scholar
  27. Chaves  SS, Pérez  A, Farley  MM, Miller  L, Schaffner  W, Lindegren  ML, The burden of influenza hospitalizations in infants from 2003 to 2012, United States. Pediatr Infect Dis J. 2014;33:9129. DOIPubMedGoogle Scholar
  28. Dawood  FS, Kamimoto  L, D’Mello  TA, Reingold  A, Gershman  K, Meek  J, Children with asthma hospitalized with seasonal or pandemic influenza, 2003–2009. Pediatrics. 2011;128:e2732. DOIPubMedGoogle Scholar
  29. Jhung  MA, D’Mello  T, Pérez  A, Aragon  D, Bennett  NM, Cooper  T, Hospital-onset influenza hospitalizations—United States, 2010–2011. Am J Infect Control. 2014;42:711. DOIPubMedGoogle Scholar
  30. Greenbaum  A, Chaves  SS, Pérez  A, Aragon  D, Bandyopadhyay  A, Bennett  N, Heavy alcohol use as a risk factor for severe outcomes among adults hospitalized with laboratory-confirmed influenza, 2005–2012. Infection. 2014;42:16570. DOIPubMedGoogle Scholar
  31. Fleming-Dutra  KE, Taylor  T, Link-Gelles  R, Garg  S, Jhung  MA, Finelli  L, Effect of the 2009 influenza A(H1N1) pandemic on invasive pneumococcal pneumonia. J Infect Dis. 2013;207:113543 . DOIPubMedGoogle Scholar
  32. Vandermeer  ML, Thomas  A, Kamimoto  L, Reingold  A, Gershman  K, Meek  J, Association between statins and mortality among patients hospitalized with lab-confirmed influenza infections: a multi-state study. J Infect Dis. 2012;205:139 . DOIPubMedGoogle Scholar
  33. Fedson  DS. Treating influenza with statins and other immunomodulatory agents. Antiviral Res. 2013;99:41735. DOIPubMedGoogle Scholar
  34. Tam  K, Yousey-Hindes  K, Hadler  JL. Influenza-related hospitalization of adults associated with low census tract socioeconomic status and female sex in New Haven County, Connecticut, 2007–2011. Influenza Other Respir Viruses. 2014;8:274–81.
  35. Yousey-Hindes  KM, Hadler  J. Neighborhood socioeconomic status and influenza hospitalizations among children: New Haven County, Connecticut, 2003–2010. Am J Public Health. 2011;101:17859. DOIPubMedGoogle Scholar
  36. Dawood  FS, Chaves  SS, Pérez  A, Reingold  A, Meek  J, Farley  MM, Complications and associated bacterial co-infections among children hospitalized with seasonal or pandemic influenza, United States, 2003–2010. J Infect Dis. 2014;209:68694. DOIPubMedGoogle Scholar
  37. Reed  C, Chaves  SS, Pérez  A, D’Mello  T, Daily Kirley  P, Aragon  D, Complications among adults hospitalized with influenza: a comparison of seasonal influenza and the 2009 H1N1 pandemic. Clin Infect Dis. 2014;59:16674. DOIPubMedGoogle Scholar
  38. Su  S, Chaves  SS, Pérez  A, D'Mello  T, Kirley  PD, Yousey-Hindes  K, Comparing clinical characteristics between hospitalized adults with laboratory-confirmed influenza A and B virus infection. Clin Infect Dis. 2014;59:2525. DOIPubMedGoogle Scholar
  39. Chaves  SS, Aragon  D, Bennett  N, Cooper  T, D’Mello  T, Farley  M, Patients hospitalized with laboratory-confirmed influenza during the 2010–2011 influenza season: exploring disease severity by virus type and subtype. J Infect Dis. 2013;208:130514. DOIPubMedGoogle Scholar
  40. Poritz  MA, Blaschke  AJ, Byington  CL, Meyers  L, Nilsson  K, Jones  DE, FilmArray, an automated nested multiplex PCR system for multi-pathogen detection: development and application to respiratory tract infection. PLoS ONE. 2011;6:e26047. DOIPubMedGoogle Scholar

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Page updated: August 12, 2015
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The conclusions, findings, and opinions expressed by authors contributing to this journal do not necessarily reflect the official position of the U.S. Department of Health and Human Services, the Public Health Service, the Centers for Disease Control and Prevention, or the authors' affiliated institutions. Use of trade names is for identification only and does not imply endorsement by any of the groups named above.
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