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Volume 22, Number 4—April 2016
Research

Quantifying Transmission of Clostridium difficile within and outside Healthcare Settings

David P. DurhamComments to Author , Margaret A. Olsen, Erik R. Dubberke, Alison P. Galvani, and Jeffrey P. Townsend
Author affiliations: Yale School of Public Health, New Haven, Connecticut, USA (D.P. Durham, A.P. Galvani, J.P. Townsend); Washington University School of Medicine, St. Louis, Missouri, USA (M.A. Olsen, E.R. Dubberke)

Main Article

Figure 2

Transitions between settings (hospital, LTCF, and the non–healthcare community) for model structure of Clostridium difficile infection (CDI). Transitions were parameterized at demographically calibrated, age-specific rates. Hospitalized patients with CDI who were given a diagnosis are subject to enhanced isolation protocols that reduce transmission. All hospitalized CDI patients are discharged at a slower rate than non–CDI patients, which reflects longer hospitalization attributable to CDI. N, p

Figure 2. Transitions between settings (hospital, LTCF, and the non–healthcare community) for model structure of Clostridium difficile infection (CDI). Transitions were parameterized at demographically calibrated, age-specific rates. Hospitalized patients with CDI who were given a diagnosis are subject to enhanced isolation protocols that reduce transmission. All hospitalized CDI patients are discharged at a slower rate than non–CDI patients, which reflects longer hospitalization attributable to CDI. N, patients not receiving antimicrobial drugs; A, patients receiving antimicrobial drugs; O, patients with a recent history of receiving antimicrobial drugs; U, uncolonized patients; C, asymptomatically colonized patients; RC, symptomatically infected patients or colonized patients and subject to recurrence; LTCF, long-term care facility. Solid arrows indicate changes in individual epidemiologic status and patient movement between the hospital, community, and LTCF. Dashed arrows indicate isolation of CDI patients.

Main Article

Page created: March 15, 2016
Page updated: March 15, 2016
Page reviewed: March 15, 2016
The conclusions, findings, and opinions expressed by authors contributing to this journal do not necessarily reflect the official position of the U.S. Department of Health and Human Services, the Public Health Service, the Centers for Disease Control and Prevention, or the authors' affiliated institutions. Use of trade names is for identification only and does not imply endorsement by any of the groups named above.
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