Volume 22, Number 6—June 2016
Dispatch
Changes in Childhood Pneumonia Hospitalizations by Race and Sex Associated with Pneumococcal Conjugate Vaccines
Andrew D. Wiese
, Carlos G. Grijalva, Yuwei Zhu, Edward F. Mitchel, and Marie R. Griffin
, Carlos G. Grijalva, Yuwei Zhu, Edward F. Mitchel, and Marie R. Griffin
Table
Pre-PCV7 and post-PCV13 annualized pneumonia rates, by age, sex, and race, and hospitalizations per 1,000 children, Tennessee, USA, 1998–2013*
| Patient age, y, and race | Patient sex | Hospitalizations/1,000 children |
Post-PCV13 vs. pre-PCV7 |
|||
|---|---|---|---|---|---|---|
| Pre-PCV7, 1998–1999, 11,059 hospitalizations | Post-PCV13, 2011–2013, 9,171 hospitalizations | Rate ratio (95% CI) | Rate difference (95% CI)† | |||
| All‡ |
4.0 |
2.0 |
0.51 (0.50–0.52) |
−2.0 (−2.1 to −1.9) |
||
| <2‡ | 18.4 | 7.3 | 0.40 (0.38–0.41) | −11.1 (−11.6 to −10.6) | ||
| Black | M | 27.1 | 8.5 | 0.31 (0.28–0.35) | −18.6 (−20.5 to −16.6) | |
| Black | F | 20.0 | 6.4 | 0.32 (0.28–0.37) | −13.6 (−15.3 to −11.9) | |
| White | M | 18.0 | 7.8 | 0.43 (0.40–0.46) | −10.2 (−11.1 to −9.3) | |
| White |
F |
14.5 |
6.2 |
0.43 (0.40–0.47) |
−8.2 (−9.0 to −7.4) |
|
| 2–4‡ | 5.4 | 3.0 | 0.56 (0.52–0.59) | −2.4 (−2.6 to −2.1) | ||
| Black | M | 6.6 | 3.4 | 0.50 (0.43–0.59) | −3.3 (−4.1 to −2.5) | |
| Black | F | 5.3 | 3.1 | 0.58 (0.49–0.70) | −2.2 (−3.0 to −1.5) | |
| White | M | 5.3 | 3.0 | 0.56 (0.51–0.62) | −2.3 (−2.7 to −1.9) | |
| White |
F |
5.0 |
2.9 |
0.59 (0.53–0.65) |
−2.0 (−2.4 to −1.6) |
|
| 5–17‡ | 1.6 | 1.1 | 0.67 (0.63–0.70) | −0.5 (−0.6 to −0.5) | ||
| Black | M | 2.0 | 1.1 | 0.57 (0.49–0.65) | −0.8 (−1.1 to −0.6) | |
| Black | F | 1.6 | 1.0 | 0.61 (0.53–0.71) | −0.6 (−0.8 to −0.4) | |
| White | M | 1.6 | 1.1 | 0.70 (0.65–0.75) | −0.5 (−0.6 to −0.4) | |
| White | F | 1.6 | 1.2 | 0.74 (0.68–0.80) | −0.4 (−0.5 to −0.3) | |
*PCV7, 7-valent pneumococcal conjugate vaccine; PCV13, 13-valent pneumococcal conjugate vaccine.
†For hospitalizations per 1,000 children.
‡Includes all race/ethnicity categories (black, white, Hispanic, other). These estimates were not different from estimates including only black and
white children.
Page created: August 18, 2016
Page updated: August 18, 2016
Page reviewed: August 18, 2016
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