Volume 22, Number 7—July 2016
Dispatch
Clinical Manifestations of Senecavirus A Infection in Neonatal Pigs, Brazil, 2015
Raquel A. Leme1, Thalita E.S. Oliveira1, Brígida K. Alcântara, Selwyn A. Headley, Alice F. Alfieri, Ming Yang, and Amauri A. Alfieri
Table 2
Distribution of nucleic acid and antigens of Senecavirus A in 1–5-day-old piglets, Brazil, 2015*
| Farm, piglet no. | Identification of Senecavirus A |
||
|---|---|---|---|
| Organs | RT-PCR | IHC | |
| A | |||
| 1 | Tongue | + | + |
| Gingiva | +† | + | |
| Ruptured cutaneous vesicle (thorax) | + | – | |
| Coronary band ulcerations | + | ND | |
| Myocardium | +† | – | |
| Lung | + | – | |
| Liver | – | – | |
| Renal pelvis | +† | + | |
| Cerebrum | – | +§ | |
| Cerebellum | + | – | |
| Brainstem | – | – | |
| 2 | Tongue | + | + |
| Myocardium | +†,‡ | – | |
| Lung | + | – | |
| Liver | + | – | |
| Renal pelvis | +† | + | |
| Cerebrum | – | +§ | |
| Cerebellum | + | – | |
| Brainstem |
+ |
– |
|
| B | |||
| 3 | Tongue | + | + |
| Coronary band ulceration | + | ND | |
| Myocardium | +† | – | |
| Lung | + | – | |
| Liver | + | – | |
| Renal pelvis | +† | + | |
| Brain | – | + | |
| Cerebellum | + | – | |
| Brainstem | + | – | |
| 4 | Tongue | + | + |
| Gingiva | +† | + | |
| Myocardium | +† | – | |
| Lung | + | – | |
| Liver | + | – | |
| Renal pelvis | +†,‡ | + | |
| Cerebrum | + | +§ | |
| Cerebellum | + | – | |
| Brainstem |
+† |
– |
|
| C, 5 | Myocardium | + | – |
| Lung | +†,‡ | – | |
| Liver | – | – | |
| Small intestine with fecal content |
+ |
+ |
|
| D, 6 |
Small intestine with fecal content |
+†,‡ |
+ |
| E | |||
| 7 | Myocardium | – | – |
| Lung | – | – | |
| Spleen | +† | – | |
| Renal pelvis | – | + | |
| Urinary bladder | + | + | |
| Small intestine with fecal content | – | – | |
| Cerebrum | – | +§ | |
| Cerebellum | – | – | |
| Brainstem | – | – | |
| 8 | Myocardium | + | – |
| Lung | +† | – | |
| Spleen | + | – | |
| Renal pelvis | + | + | |
| Urinary bladder | + | + | |
| Small intestine with fecal content | – | – | |
| Cerebrum | + | +§ | |
| Cerebellum | + | – | |
| Brainstem | – | – | |
| 9 | Gingiva | + | + |
| Myocardium | + | – | |
| Lung | + | – | |
| Spleen | + | – | |
| Renal pelvis | + | + | |
| Urinary bladder | +† | + | |
| Small intestine with fecal content | + | – | |
| Cerebrum | – | +§ | |
| Cerebellum | – | – | |
| Brainstem | + | – | |
| 10 | Tongue | +†,‡ | + |
| Gingiva | + | + | |
| Myocardium | + | – | |
| Lung | + | – | |
| Spleen | + | – | |
| Renal pelvis | + | + | |
| Urinary bladder | + | + | |
| Small intestine with fecal content | + | – | |
| Cerebrum | + | +§ | |
| Cerebellum | + | – | |
| Brainstem | – | – | |
*IHC, immunohistochemistry; ND, not done; RT-PCR, reverse transcription PCR; +, positive; –, negative.
†Amplicons submitted for sequence analysis.
‡Amplicons representative of each farm in the phylogenetic tree construction.
§Choroid plexus.
1These authors contributed equally to this article.
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