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Volume 22, Number 7—July 2016
Research

High Incidence of Chikungunya Virus and Frequency of Viremic Blood Donations during Epidemic, Puerto Rico, USA, 2014

Graham SimmonsComments to Author , Vanessa Brès, Kai Lu, Nathan M. Liss, Donald J. Brambilla, Kyle R. Ryff, Roberta Bruhn, Edwin Velez, Derrek Ocampo, Jeffrey M. Linnen, Gerardo Latoni, Lyle R. Petersen, Phillip Williamson, and Edward L. Murphy
Author affiliations: Blood Systems Research Institute, San Francisco, California, USA (G. Simmons, K. Lu, N.M. Liss, R. Bruhn, M.P. Busch); University of California, San Francisco (G. Simmons, M.P. Busch); Hologic, Inc., San Diego, California, USA (V. Brès, D. Ocampo, J.M. Linnen); RTI International, Rockville, Maryland, USA (D.J. Brambilla); Puerto Rico Department of Health, San Juan, Puerto Rico, USA (K.R. Ryff); Banco de Sangre de Servicios Mutuos, San Juan, Puerto Rico, USA (E. Velez, G. Latoni); Centers for Disease Control and Prevention, Fort Collins, Colorado, USA (L.R. Petersen); Creative Testing Solutions, Tempe, Arizona, USA (P.C. Williamson)

Main Article

Table 2

Individual blood donations tested for chikungunya virus by nucleic acid amplification testing and serologic analysis during a chikungunya epidemic, Puerto Rico, USA, 2014*

Month No. samples No. ID-NAAT reactive samples ID-NAAT yield, % No. reactive at 1:16 dilution (MP-NAAT) IgM reactive
 IgG reactive
Total IgM+/ID-only reactive Total IgG+/ID-only reactive
September 987 18 1.8 8 11 7† 8 7‡
October 1,010 21 2.1 9 15 10 14 10
November 1,010 17 1.7 4 16 12 14 12
Total 3,007 56 1.9 21 42 32† 36 32‡

*ID, individual donor; NAAT, nucleic acid amplification testing; MP, minipool.
†Includes 1 IgM-positive/IgG-negative ID-only positive specimen.
‡Includes one IgM-negative/IgG-positive ID-only positive specimen.

Main Article

Page created: June 14, 2016
Page updated: June 14, 2016
Page reviewed: June 14, 2016
The conclusions, findings, and opinions expressed by authors contributing to this journal do not necessarily reflect the official position of the U.S. Department of Health and Human Services, the Public Health Service, the Centers for Disease Control and Prevention, or the authors' affiliated institutions. Use of trade names is for identification only and does not imply endorsement by any of the groups named above.
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