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Volume 22, Number 9—September 2016
Letter

Fluoroquinolone-Resistant Mycoplasma genitalium, Southwestern France

Chloé Le Roy, Nadège Hénin, Sabine Pereyre, and Cécile BébéarComments to Author 
Author affiliations: University of Bordeaux, Bordeaux, France (C. Le Roy, N. Hénin, S. Pereyre, C. Bébéar); Institut National de la Recherche Agronomique, Villenave d'Ornon, France (C. Le Roy, N. Hénin, S. Pereyre, C. Bébéar); Bordeaux University Hospital, Bordeaux (S. Pereyre, C. Bébéar)

Main Article

Table

Fluoroquinolone resistance–associated amino acid changes in GyrA and ParC and macrolide resistance–associated mutations in the 23S rRNA gene in Mycoplasma genitalium, France, 2013–2014*

Patient no. Date of collection Patient sex Specimen type Mutation in the 23S rRNA gene Amino acid changes in
GyrA ParC
1 2013 Jan 9 F Vaginal swab A2058G/A2059G NA NA
2 2013 Feb 1 F Vaginal swab A2058G
3 2013 Feb 1 M Urethral swab A2058G/A2059G Ala-93→Thr
4 2013 Feb 18 M Urethral swab A2058G/A2059G
5 2013 Feb 20 M Urine A2058G/A2059G
6 2013 Mar 11 M Urine A2058G/A2059G Asp-84→Tyr
7 2013 Mar 28 F Vaginal swab A2058G/A2059G NA
8 2013 Apr 3 M Urine Wild-type Asp-84→Tyr
9 2013 Apr 8 F Vaginal swab A2058G/A2059G
10 2013 Apr 11 F Vaginal swab A2058G/A2059G NA NA
11 2013 Apr 16 F Vaginal swab A2058G NA
12 2013 Apr 19 F Vaginal swab Wild-type Ser-80→Asn
13 2013 May 21 M Urethral swab A2059G
14 2013 Jul 4 M Urine A2059G
15 2013 Jul 4 M Urethral swab A2059G
2013 Jul 19 M Urine A2059G
16 2013 Jul 19 M Urine A2058G
17 2013 Aug 9 F Vaginal swab A2059G NA
18 2013 Sep 30 F Vaginal swab A2058G/A2059G
19 2013 Sep 30 F Vaginal swab A2058G/A2059G
20 2013 Oct 29 F Vaginal swab Wild-type Asn-96→Ser
21 2013 Nov 22 F Vaginal swab A2058G/A2059G NA NA
22 2013 Nov 29 F Vaginal swab A2062T
23 2013 Dec 1 F Vaginal swab Wild-type Asp-84→Tyr
24 2014 Jan 21 F Vaginal swab A2059G
25 2014 Jan 29 F Vaginal swab A2059G
26 2014 Jan 30 F Vaginal swab A2058G/A2059G NA
27 2014 Feb 13 F Vaginal swab A2059G
28 2014 Feb 18 M Urine Wild-type Ser-80→Ile
29 2014 Feb 24 F Vaginal swab Wild-type Asp-84→Asn
30 2014 Mar 5 F Vaginal swab Wild-type Asp-84→Asn
31 2014 Mar 14 M Urine NA Ser-80→Asn
32 2014 Apr 3 F Endocervical swab A2058G
33 2014 Apr 7 M Urethral swab A2059G
34 2014 Jun 24 F Vaginal swab A2059C
35 2014 Jul 9 F Endocervical swab A2059G NA
36 2014 Jul 25 F Urine A2058G/A2059G NA NA
37 2014 Jul 25 F Vaginal swab A2058G
38 2014 Aug 19 F Endocervical swab A2062T NA
39 2014 Aug 28 F Vaginal swab A2058G/A2059G
40 2014 Sep 24 F Vaginal swab A2059G
41 2014 Oct 7 F Vaginal swab A2059G
42 2014 Oct 15 F Vaginal swab A2058G/A2059G
43 2014 Oct 31 M Urine A2058G
44 2014 Nov 5 F Vaginal swab A2058G/A2059G NA
45 2014 Nov 28 F Vaginal swab A2058G
46 2014 Dec 3 F Vaginal swab Wild-type Asp-84→Asn
47 2014 Dec 3 M Urethral swab Wild-type Asp-84→Asn
48
2014 Dec 4
M
Urine
A2059G


*A2058/A2059G indicates a macrolide–resistant (A2058G or A2059G) genotype. Positions in the 23S rRNA and in GyrA and ParC are identified according to Escherichia coli numbering. NA, not available; –, no amino acid change.

Main Article

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Page updated: August 16, 2016
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