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Volume 4, Number 1—March 1998

Perspective

Risk for Transfusion-Transmitted Infectious Diseases in Central and South America

Gabriel A. Schmunis, Fabio Zicker, Francisco Pinheiro, and David Brandling-Bennett
Author affiliations: Pan American Health Organization, Washington, D.C., USA

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Table 2

Probability of receiving an infected transfusion P(R)a and probability of getting a transfusion-transmitted infection P(I)b, by countryc

HIV (x104)
HBV (x104)
HCV (x104)
T. cruzi (x104)
Country P(R) P(I) P(R) P(I) P(R) P(I) P(R) P(I)
Bolivia 0.64 0.57 17.27 12.95 NSPd NSP 1096.38 219.28
Chile 0.00 0.00 0.26 0.20 46.46 41.82 29.36 5.87
Colombia 0.24 0.22 1.20 0.90 74.55 67.09 124.24 24.85
Costa Rica 0.00 0.00 0.45x 0.34 NSP NSP NSP NSP
Ecuador 1.05 0.95 4.52 3.39 10.33 9.38 10.29 2.06
El Salvador 0.00 0.00 3.23 2.42 18.87 16.97 88.75 17.75
Guatemala 0.00 0.00 14.28 10.71 55.26 49.74 36.75 7.35
Honduras 0.00 0.00 4.49 3.37 3.97 3.57 13.02x 2.60
Nicaragua 0.00 0.00 18.95 14.21 22.70 20.43 10.48 2.10
Paraguay 0.00 0.00 9.32 6.99 NSP NSP 62.37 12.47
Peru 0.00 0.00 0.87x 0.65 20.62 18.56 247.80 49.56
Venezuela 0.00 0.00 1.45x 1.09 71.35 64.21 13.86 x 2.77

aP(R) = probability of receiving an infected transfusion = prevalence of infection x 1- level of screening; xfor countries in which reported screening level was 100%, a residual P(R) was estimated as prevalence x 1- screening sensitivity rate x 10,000.
bP(I) = probability of getting a transfusion-transmitted infection = P(R) x infectivity index (infectivity indexes used were HIV=90%; HBV=75%; HCV=90%; T.cruzi=20%). For calculations of P(R) and P(I) the prevalence was corrected taking into account the sensitivity of the screening.
cData from 1993, except for Ecuador and Paraguay, which were for 1994.
dNo screening performed, so P(R) and P(I) not known.

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