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Volume 4, Number 1—March 1998

Perspective

Risk for Transfusion-Transmitted Infectious Diseases in Central and South America

Gabriel A. Schmunis, Fabio Zicker, Francisco Pinheiro, and David Brandling-Bennett
Author affiliations: Pan American Health Organization, Washington, D.C., USA

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Table 3

Estimates of transfusion-transmitted infectious diseases, by countrya

Country No. of donors Absolute no. of transfusion-
transmitted infectious diseasesb Infection spreading indexc/104 Ratio of infections: donations
HIV HBV HCV T. cruzi Total
Bolivia 37,948 2 49 NAe 832 883 233 1:43
Chiled 217,312 0 8 1681 236 1925 88 1:113
Colombia 352,316 8 32 2364 875 3279 93 1:107
Costa Rica 50,692 0 2f NA NA NA NA NA
Ecuador 98,473 9 33 92 20 154 16 1:639
El Salvador 48,048 0 12 82 85 179 37 1:268
Guatemala 45,426 0 49 226 33 308 68 1:147
Honduras 27,885 0 9 10 7f 26 9 1:1072
Nicaragua 46,001 0 65 94 10 169 37 1:272
Paraguay 32,893 0 23 NA 41 64 19 1:514
Perug 52,909 0 4f 147 393 544 103 1:97
Venezuela 204,316 0 22f 1312 57f 1391 68 1:147

aData from 1993 except for Ecuador and Paraguay, which were for 1994.
bNumber of cases transmitted by blood transfusion = [number of donors x P(I) ]. For calculations of number of infections, the prevalence was corrected taking into account the sensitivity of the screening.
cInfection spreading index = (total number of infections transmitted ¸ number of donors) x 10,000.
dFractionation index = 1.85.
eData not available.
fResidual infectivity considering that sensitivity of diagnostic tests is not 100%.
gFractionation index = 1.5.

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