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Volume 4, Number 2—June 1998

Perspective

Accommodating Error Analysis in Comparison and Clustering of Molecular Fingerprints

Hugh Salamon*, Mark R. Segal*, Alfredo Ponce de Leon†, and Peter M. Small‡
Author affiliations: *University of California, San Francisco, California, USA; †Instituto Nacional Nutrición, Zubriran, Mexico City, Mexico; ‡Stanford University Medical Center, Stanford, California, USA

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Table 1

Pairwise comparisons (n=6,641) of lanes across gels characterize unaligned proportional error and residual error

H37Rv band b* Mean kilo-bases wb Unaligned pairwise proportional error
Aligned pairwise proportional error
mean
r(b) s.d. mean
ra(b) s.d.
1 5.029 0.0253 0.0196 0.0099 0.0079
2 4.853 0.0249 0.0202 0.0084 0.0075
3 3.533 0.0253 0.0303 0.0109 0.0203
4 2.814 0.0237 0.0283 0.0105 0.0182
5 2.153 0.0202 0.0186 0.0086 0.0125
6 1.892 0.0210 0.0204 0.0100 0.0085
7 1.800 0.0226 0.0220 0.0092 0.0082
8 1.684 0.0227 0.0193 0.0083 0.0083
9 1.541 0.0221 0.0198 0.0079 0.0081
10 1.397 0.0225 0.0200 0.0093 0.0078
11 1.314 0.0231 0.0200 0.0111 0.0090
12 0.936 0.0281 0.0249 0.0142 0.0157
mean 0.0235 0.0219 0.0099 0.0110

*Symbols as in Appendix.

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