Volume 5, Number 3—June 1999
Synopsis
Adhesins as Targets for Vaccine Development
Theresa M. Wizemann, John E. Adamou, and Solomon Langermann
Table 2
Adhesins of gram-positive bacteria
| Adhesin | Strain | Ligand | Reference |
|---|---|---|---|
| Antigen I/II | Family Demuth (39) | ||
| Ag I/II, SpaP, | |||
| P1, PAc | Streptococcus mutans | Salivary glycoprotein | |
| SspA, SspB | Streptococcus gordonii | Salivary glycoprotein Actinomyces | |
| SpaA, PAg | Streptococcus sobrinus | Salivary glycoprotein | |
| CshA , CshB | S. gordonii | Actinomyces, fibronectin | McNab (40) |
| FnbA, FnbB | Staphylococcus aureus | Fibronectin | Jonsson (41) |
| SfbI, Protein F | Streptococcus pyogenes | Fibronectin | Talay (42) Hanski (43) |
| LraI gamily | Burnett-Curley et al. (44) | ||
| Jenkinson and Lamont (12) | |||
| FimA | Streptococcus parasanguis | Salivary glycoprotein fibrin | |
| PsaA | Streptococcus pneumoniae | Unknown | |
| ScaA | S. gordonii | Actinomyces | |
| SsaB | Streptococcus sanguis | Salivary glycoprotein | |
| EfaA | Enterococcus faecalis | Unknown | |
| CbpA/SpsA/PbcA/ PspC | S. pneumoniae | Cytokine activated epithelial and endothelial cells, IgA | Rosenow (45) Hammerschmidt et al. (46) Briles et al. (47) Smith et al. (48) |
