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Volume 6, Number 3—June 2000

Dispatch

Mycobacterium tuberculosis Beijing Genotype Emerging in Vietnam

Dang Duc Anh*, Martien W. Borgdorff†, L.N. Van‡, N.T.N. Lan§, Tamara van Gorkom¶, Kristin Kremer¶, and Dick van Soolingen¶Comments to Author 
Author affiliations: *National Institute of Hygiene and Epidemiology, Hanoi, Vietnam; †Royal Netherlands Tuberculosis Association, The Hague, The Netherlands; ‡National Institute of Tuberculosis and Respiratory Diseases, Hanoi, Vietnam; §Tuberculosis and Lung Diseases Center, Ho Chi Minh City, Vietnam; and ¶National Institute of Public Health and the Environment, Bilthoven, The Netherlands

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Table 2

Risk factors for drug resistance in 499 new tuberculosis cases in Ho Chi Minh City

Resistance (%)
ORa (95% CIb)
Genotype No. INH SM RIF EMB MDR INH SM
Beijing 264 28 42 3 3 3 1.7 (1.1-2.6) 3.1 (2.0-4.6)
Other 235 19 19 2 1 2 1 (p<0.05) 1 (p<0.001)
Age group
<25 66 17 36 3 0 3 1 (p>0.05) 1 (p>0.05)
25-34 165 27 32 3 2 3 1.8 (0.9-3.8) 0.8 (0.4-1.5)
35-44 147 25 33 1 1 1 1.7 (0.8-3.5) 0.8 (0.5-1.6)
45-54 59 19 25 3 5 3 1.1 (0.5-2.9) 0.6 (0.3-1.3)
55-64 30 23 23 3 3 3 1.5 (0.5-4.4) 0.5 (0.2-1.4)
65+ 32 31 31 0 0 0 2.3 (0.8-6.1) 0.8 (0.3-2.0)
BCG scar
Yes 259 22 31 3 2 3 1(P>0.05) 1 (P>0.05)
No 402 73 22 2 2 2 1.3 (0.9-2.0) 1.1 (0.7-1.6)
Total 499 24 31 2 2 2

aOR, odds ratio.
bCI, confidence interval.
INH, isoniazide; SM, streptomycin; RIF, rifampin; EMB, ethambutol; MDR, multidrug resistant

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