Volume 6, Number 5—October 2000
Dispatch
Antimicrobial-Drug Use and Changes in Resistance in Streptococcus pneumoniae
Daniel J. Diekema
, Angela B. Brueggemann, and Gary V. Doern
, Angela B. Brueggemann, and Gary V. DoernTable 2
Prescriptions for antibiotics at medical centers with high, intermediate, and low antimicrobial-drug usea
| Class/tertile | Mean | Median | Range | SD |
|---|---|---|---|---|
| Beta-lactams | ||||
| High | 1,640 | 1,620 | 1,186-2,557 | 411 |
| Intermediate | 1,027 | 1,040 | 948-1,136 | 69 |
| Low | 859 | 870 | 777-917 | 51 |
| Macrolides | ||||
| High | 929 | 865 | 800-1,286 | 166 |
| Intermediate | 738 | 722 | 687-787 | 35 |
| Low | 609 | 623 | 528-673 | 52 |
| Quinolones | ||||
| High | 282 | 258 | 222-424 | 63 |
| Intermediate | 197 | 200 | 177-216 | 16 |
| Low | 143 | 146 | 91-170 | 27 |
| Tetracyclines | ||||
| High | 77 | 75 | 61-100 | 15 |
| Intermediate | 56 | 58 | 50-59 | 3 |
| Low | 33 | 34 | 25-45 | 7 |
aAll values are expressed in units of mean number of prescriptions per 100,000 population per month during the period between the two surveillance studies (May 1994-April 1998).
