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Volume 7, Number 1—February 2001

Perspective

Bovine Spongiform Encephalopathy and Variant Creutzfeldt-Jakob Disease: Background, Evolution, and Current Concerns

Paul Brown*Comments to Author , Robert G. Will†, Raymond Bradley‡, David M. Asher§, and Linda Detwiler¶
Author affiliations: *National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, Maryland, USA; †National Creutzfeldt-Jakob Disease Surveillance Unit, Western General Hospital, Edinburgh, Scotland; ‡Central Veterinary Laboratory, New Haw, Addlestone, UK; §Center for Biologics Evaluation and Research, Food and Drug Administration, Rockville, Maryland, USA; ¶Animal and Plant Health Inspection Service, U.S. Department of Agriculture, Robbinsville, New Jersey, USA

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Table 1

Reported cases of bovine spongiform encephalopathy in the United Kingdom and other countries (as of

December 2000)a
Country Native cases Imported cases Total cases
United Kingdom 180,376b 0 180,376
Republic of Ireland 487 12 499
Portugal 446 6 452
Switzerlandc 363 0 363
Francec 150 1 151
Belgium 18 0 18
Netherlands 6 0 6
Liechtenstein 2 0 2
Denmark 1 1 2
Luxembourg 1 0 1
Germany 3 6 9
Oman 0 2 2
Italy 0 2 2
Spaind 0 2 2
Canada 0 1 1
Falklands (UK) 0 1 1
Azores (Portugal)e 0 1 1

aData from Organization of International Epizootics(Paris) and Ministry of Agriculture, Fisheries, and Food (UK).
bIncludes 1,287 cases in offshore British islands.
cIncludes cases detected by active surveillance with immunologic methods.
dOrigin and dates of imported cases are under investigation.
eCase imported from Germany.

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