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Volume 8, Number 1—January 2002

Research

Antimicrobial Drug Resistance in Pathogens Causing Nosocomial Infections at a University Hospital in Taiwan, 1981-1999

Po-Ren Hsueh*†, Mei-Ling Chen*†, Chun-Chuan Sun†, Wen-Hwei Chen†, Hui-Ju Pan*†, Li-Seh Yang†, Shan-Chwen Chang*†, Shen-Wu Ho*†, Chin-Yu Lee†, Wei-Chuan Hsieh†, and Kwen-Tay Luh*†Comments to Author 
Author affiliations: *National Taiwan University College of Medicine, Taipei, Taiwan; †National Taiwan University Hospital, Taipei, Taiwan;

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Table 2

Selected antimicrobial resistant pathogens associated with nosocomial infection at National Taiwan University Hospital from 1981 to 1999

Resistant pathogen% resistance (all patients/in intensive care unit patients/in patients in general wards)
1981-19861987-19921993-19981999
Methicillin-resistant Staphylococcus aureus20.2/27.8/19.531.4/58.5/26.664.8/86.9/56.769.3/87.4/60.2
Methicillin-resistant CoNSa72.2/88.2/70.874.0/83.9/71.579.0/88.7/75.190.6/90.9/90.5
Penicillin-resistant enterococci5.9/6.8/5.820.7/30/19.619.5/22.6/18.735.9/40.9/27.8
Gentamicin-resistant enterococci0.0/0.0/0.071.0/71.4/70.961.5/67.2/60.050.0/39.3/55.2
Cefotaxime-resistant Escherichia coli1.6/0.0/1.72.8/8.6/2.56.8/13.1/6.212.3/10.3/12.7
Cefotaxime-resistant Klebsiella pneumoniae4.9/8.8/3.97.4/16.9/5.622.8/50.5/15.616.5/40.0/9.3
Cefotaxime-resistant Enterobacter spp.35.8/52.4/32.449.7/55.7/47.757.6/67.0/53.650.9/61.8/46.2
Cefotaxime-resistant Pseudomonas aeruginosa24.2/20.0/25.016.1/24.3/12.110.2/16.9/7.811.2/17.6/8.1
Imipenem-resistant P. aeruginosaNANA8.5/18.2/4.96.7/4.5/7.7
Ciprofloxacin-resistant P. aeruginosaNANA8.7/11.6/5.814.0/18.2/2.9
Imipenem-resistant Acinetobacter baumanniiNANA6.7/9.1/4.412.5/23.3/7.6

aCoNS = coagulase-negative staphylococci; NA = not available.

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