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Volume 9, Number 1—January 2003

Research

Epidemic Hand, Foot and Mouth Disease Caused by Human Enterovirus 71, Singapore

Kwai Peng Chan*Comments to Author , Kee Tai Goh†, Chia Yin Chong‡, Eng Swee Teo§, Gilbert Lau§, and Ai Ee Ling*
Author affiliations: *Singapore General Hospital, Singapore, Republic of Singapore; †National Environment Agency, Singapore, Republic of Singapore,; ‡Kandang Kerbau Women’s and Children’s Hospital, Singapore, Republic of Singapore; §Centre for Forensic Medicine, Health Sciences Authority, Singapore, Republic of Singapore

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Table 2

Viruses isolated from HFMD cases during the epidemica

Virus
No. HFMD patients (%)
No. non-HFMD patients (%)
HEV71
HEV71 only
HEV71 + EV25
HEV71 + Rhinovirus
HEV71 + CMV 76 (73.1)
73
1
1
1 5 (29.4)
5
0
0
0
CAV4
1 (1.0)
0
CAV6
4 (3.8)
0
CAV10
3 (2.9)
1 (5.9)
CAV16
5 (4.8)
0
CAV24
4 (3.8)
3 (17.6)
CBV3
1 (1.0)
1 (5.9)
CBV4
1 (1.0)
2 (11.8)
CBV5
1 (1.0)
3 (17.6)
EV18
4 (3.8)
0
CMV
4 (3.8)
0
Herpes simplex virus 1
0
2 (11.8)
Total 104 (100.0) 17 (100.0)

aHFMD, hand, foot and mouth disease; HEV, human enterovirus; EV, echovirus; CMV, Cytomegalovirus; CAV, coxsackie virus A; CBV, coxsackie virus B.

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