Mass Antibiotic Treatment for Group A Streptococcus Outbreaks in Two Long-Term Care Facilities1
Andrea Smith*†, Aimin Li‡, Ornella Tolomeo*, Gregory J. Tyrell§†, Frances Jamieson‡, and David Fisman*¶
Author affiliations: *City of Hamilton Social and Public Health Services Department, Hamilton, Ontario, Canada; †University of Alberta, Edmonton, Alberta; ‡Canada Ontario Ministry of Health and Long-Term Care, Toronto, Ontario, Canada; §Provincial Laboratory for Public Health, Edmonton, Alberta, Canada; ¶McMaster University, Hamilton, Ontario, Canada
Figure 2. Epidemic curve for outbreak 1. Clinical cases (black bars) of invasive GAS infection occurred at intervals of 3 to 4 months. With the occurrence of cases, acquisition of culture specimens resulted in identification of asymptomatic colonization with the outbreak strain (white bars) or unrelated strains (hatched bars) in other residents and staff. No additional clinical cases occurred after mass antibiotic treatment (M.A.T.); resident A died (†) in July 2002; colonization of two residents with the outbreak strain was recognized 1 month later.
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