Volume 9, Number 12—December 2003
Noninvasive Method for Monitoring Pneumocystis carinii Pneumonia
|Groupsb||No. points||Spearman r||95% Confidence interval||p value||Significant|
|LH Pc DNA vs. post-OS Pc DNA
||0.1648 to 0.7978
|LH Pc DNA vs. Pc nuclei
||0.7731 to 0.9606
|Post-OS Pc DNA vs. Pc Nuclei
||0.0388 to 0.7465
|Pre-OS Pc DNA vs. post-OS Pc DNA
||-0.0863 to 0.6988
|Pre-OS Pc DNA vs Pc Nuclei
||-0.0374 to 0.7232
|Pre-OS Pc DNA vs. LH Pc DNA||21||0.2939||-0.1712 to 0.6519||0.1960||No|
a21 data points were included in these analyses because 2 rats from the 10-wk group died and 1 preimmunosuppression oral swab sample in the 7-wk group was lost in processing.
bPre-OS Pc DNA, P. carinii –specific DNA from oral swabs taken prior to immunosuppression; post-OS Pc DNA, P. carinii–specific DNA from oral swabs taken at the time of euthanasia; LH Pc DNA, P. carinii–specific DNA from lung homogenates of rats at the 3 different time points; log Pc Nuclei, P. carinii organism number assessed by microscopic enumeration.