Volume 9, Number 2—February 2003
Research
Equine Amplification and Virulence of Subtype IE Venezuelan Equine Encephalitis Viruses Isolated during the 1993 and 1996 Mexican Epizootics
Dante Gonzalez*, José G. Estrada-Franco†, Anne-Sophie Carrara†, Judith F. Aronson†, and Scott C. Weaver†
Table 2
Outcome for horses experimentally infected with Venezuelan equine encephalitis virus strains
| Horse no. | Gender | Virus strain | Maximum temperature (°C) | Maximum viremia levela | Clinical outcome | Histopathologic findings |
|---|---|---|---|---|---|---|
| 1 | Male | OAX131 | 40.3 | 2.8 | No disease | Perivascular cuffing, minimal encephalitis |
| 2 | Male | OAX131 | 40.2 | 1.4 | No disease | Perivascular cuffing, minimal encephalitis |
| 3 | Male | OAX131 | 39.1 | 1.4 | No disease | Perivascular cuffing, minimal encephalitis |
| 4 | Male | CPA201 | 40.8 | 2.4 | Fatal encephalitis | Perivascular cuffing, lymphocytic meningitis, focal encephalitis |
| 5 | Male | CPA201 | 38.4 | 1.4 | No disease | Normal |
| 6 | Female | CPA201 | 37.7 | <0.6 | No disease | Normal |
| 7 | Male | OAX142 | 38.2 | <0.6 | No disease | Normal |
| 8 | Female | OAX142 | 38.9 | <0.6 | No disease | Normal |
| 9 | Male | I-290–93 | 38.6 | <0.6 | No disease | Normal |
| 10 | Male | I-290–93 | 39.8 | <0.6 | No disease | Normal |
aTiters expressed as log10 suckling mouse intracerebral lethal dose50/mL serum.
