Volume 9, Number 7—July 2003
Research
Antimicrobial Susceptibility Breakpoints and First-Step parC Mutations in Streptococcus pneumoniae: Redefining Fluoroquinolone Resistance
Sue Lim*†, Darrin Bast*†, Allison McGeer*†, Joyce de Azavedo*†, and Donald E. Low*†
Table 3
The prevalence of ParC amino acid substitutions among all strains according to their levofloxacin and ciprofloxacin MICs
| MIC (μg/mL) | No. strains with ParC amino acid substitution at 79 or 83 |
|
|---|---|---|
| Ciprofloxacin (%) | Levofloxacin (%) | |
| 2 | 4/14 (29) | 48/82 (59) |
| 4 | 24/37 (65) | 5/8 (63) |
| 8 | 11/12 (92) | 10/10 (100) |
| >8 | 22/22 (100) | 15/15 (100) |
| Total | 62/87 (71) | 78/115 (69) |
