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Volume 9, Number 7—July 2003

Research

Amoeba-Resisting Bacteria and Ventilator-Associated Pneumonia

Bernard La Scola*, Ioanna Boyadjiev*†, Gilbert Greub*, Atieh Khamis*, Claude Martin†, and Didier Raoult*†Comments to Author 
Author affiliations: *Unité des Rickettsies, Marseille, France; †Hôpital Nord, Marseille, France

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Table 1

Definition criteria for ventilator-associated pneumonia (VAP) and systemic inflammatory response syndrome (SIRS)

VAP SIRS Unexplained VAP Unexplained SIRS
New and persistent roentgenographic lung infiltrate and new onset of:
a) Increase in white blood cells >10 g/L
b) Fever or hypothermia (>38°C or <36°C)
c) Purulent sputum
d) Duration of at least 2 weeks
e) PaO2/FiO2 ratio <100 At least two of:
a) T° >38°C or <36°C
b) Heart rate >90/min
c) Respiratory rate >20/min or PaCO2 <32 mmHg
d) Leukocytes >12 or <4 g/L or immature (band) forms Lack of recovery of bacteria from:
a) Lung secretions
b) Blood cultures Lack of recovery of bacteria from:
a) Lung secretions
b) Blood cultures
c) Urine

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