Volume 10, Number 9—September 2004
Research
SpaceTime Cluster Analysis of Invasive Meningococcal Disease
Christian J.P.A. Hoebe* , Hester E. de Melker†, Lodewijk Spanjaard‡, Jacob Dankert‡^{1}, and Nico Nagelkerke†
Author affiliations: *Eastern South Limburg Municipal Public Health Service, Heerlen, the Netherlands; †National Institute of Public Health and the Environment, Bilthoven, the Netherlands; ‡Netherlands Reference Laboratory for Bacterial Meningitis, Amsterdam, the Netherlands; 1Deceased 24 January 2004.
A:4:P1.NT; n = 1  B:15:P1.NT; n = 33  B:4:P1.7,16; n = 4  C:16:P1.16; n = 1  C:NT:P1.2; n = 1 

A:NT:P1.16; n = 4  B:16:P1.1; n = 2  B:4:P1.7,9; n = 1  C:16:P1.2; n = 11  C:NT:P1.2,5; n = 5 
B:1:P1.1,7; n = 1  B:16:P1.14; n = 10  B:4:P1.9; n = 36  C:16:P1.2,5; n = 18  C:NT:P1.5; n = 20 
B:1:P1.10; n = 1  B:16:P1.16; n = 8  B:4:P1.NT; n = 455  C:16:P1.NT; n = 5  C:NT:P1.5,10; n = 1 
B:1:P1.12; n = 2  B:16:P1.2; n = 9  B:4,14:P1.14; n = 2  C:2a:P1.1;n = 1  C:NT:P1.6; n = 7 
B:1:P1.14; n = 25  B:16:P1.2,5; n = 22  B:4,14:P1.16; n = 4  C:2a:P1.16; n = 8  C:NT:P1.7; n = 7 
B:1:P1.15; n = 2  B:16:P1.2,7; n = 1  B:4,14:P1.4; n = 4  C:2a:P1.2; n = 42  C:NT:P1.7,9; n = 1 
B:1:P1.16; n = 92  B:16:P1.4; n = 1  B:4,14:P1.5; n = 1  C:2a:P1.2,5; n = 164  C:NT:P1.9; n = 1 
B:1:P1.4; n = 87  B:16:P1.5; n = 3  B:4,14:P1.9; n = 1  C:2a:P1.4; n = 4  C:NT:P1.NT; n = 9 
B:1:P1.4,14; n = 1  B:16:P1.6; n = 2  B:4,14:P1.NT; n = 4  C:2a:P1.5; n = 163  W135:2a:P1.2,5; n = 16 
B:1:P1.5; n = 15  B:16:P1.7; n = 3  B:4,15:P1.10; n = 1  C:2a:P1.6; n = 2  W135:4,15:P1.16; n = 1 
B:1:P1.5,9; n = 1  B:16:P1.7,16; n = 1  B:4,15:P1.4; n = 2  C:2a:P1.7,15; n = 1  W135:NT:P1.1,7; n = 5 
B:1:P1.6; n = 3  B:16:P1.NT; n = 9  B:4,15:P1.7; n = 1  C:2a:P1.9; n = 3  W135:NT:P1.2; n = 1 
B:1:P1.7,16; n = 7  B:2a:P1.1; n = 1  B:4,15:P1.NT; n = 1  C:2a:P1.NT; n = 44  W135:NT:P1.2,5; n = 2 
B:1:P1.9; n = 1  B:2a:P1.16; n = 1  B:4,16:P1.4; n = 1  C:2a,1:P1.16; n = 1  W135:NT:P1.5; n = 5 
B:1:P1.9,12; n = 1  B:2a:P1.2; n = 1  B:4,16:P1.7; n = 2  C:2b:P1.1; n = 1  W135:NT:P1.6; n = 25 
B:1:P1.NT; n = 61  B:2a:P1.2,5; n = 2  B:NT:P1.1; n = 3  C:2b:P1.1,7; n = 3  W135:NT:P1.NT; n = 4 
B:14:P1.1; n = 2  B:2a:P1.4,5; n = 1  B:NT:P1.1,7; n = 10  C:2b:P1.10; n = 9  X:4:P1.16; n = 3 
B:14:P1.1,7; n = 1  B:2a:P1.7,16; n = 1  B:NT:P1.10; n = 23  C:2b:P1.14; n = 2  X:4:P1.7; n = 1 
B:14:P1.12; n = 9  B:2a:P1.NT; n = 3  B:NT:P1.10,14; n = 1  C:2b:P1.15; n = 1  X:4:P1.7,15; n = 1 
B:14:P1.14; n = 2  B:2a,1:P1.2,5; n = 1  B:NT:P1.12; n = 9  C:2b:P1.16; n = 1  X:4:P1.NT; n = 1 
B:14:P1.15; n = 17  B:2a,1:P1.NT; n = 1  B:NT:P1.14; n = 23  C:2b:P1.2; n = 5  X:NT:P1.16; n = 1 
B:14:P1.16; n = 1  B:2b:P1.1,7; n = 1  B:NT:P1.15; n = 39  C:2b:P1.2,12; n = 2  Y:14:P1.14; n = 1 
B:14:P1.2,5; n = 3  B:2b:P1.10; n = 34  B:NT:P1.16; n = 20  C:2b:P1.2,5; n = 66  Y:14:P1.2,5; n = 2 
B:14:P1.4; n = 85  B:2b:P1.12; n = 1  B:NT:P1.2; n = 5  C:2b:P1.4; n = 1  Y:14:P1.5; n = 1 
B:14:P1.4,15; n = 1  B:2b:P1.15; n = 1  B:NT:P1.2,5; n = 20  C:2b:P1.5; n = 2  Y:14:P1.7,14; n = 1 
B:14:P1.4,7; n = 1  B:2b:P1.2,5; n = 8  B:NT:P1.2,7; n = 1  C:2b:P1.NT; n = 8  Y:14:P1.NT; n = 4 
B:14:P1.5; n = 4  B:2b:P1.7; n = 1  B:NT:P1.4; n = 102  C:4:P1.1; n = 16  Y:15:P1.16; n = 1 
B:14:P1.5,10; n = 1  B:2b:P1.NT; n = 9  B:NT:P1.4,12; n = 2  C:4:P1.1,7; n = 1  Y:15:P1.5; n = 1 
B:14:P1.6; n = 1  B:4:P1.1; n = 4  B:NT:P1.4,7; n = 2  C:4:P1.10; n = 5  Y:4:P1.5; n = 7 
B:14:P1.7; n = 1  B:4:P1.1,7; n = 15  B:NT:P1.5; n = 8  C:4:P1.14; n = 1  Y:4:P1.NT; n = 1 
B:14:P1.7,16; n = 1  B:4:P1.10; n = 205  B:NT:P1.6; n = 30  C:4:P1.15; n = 4  Y:4,14:P1.5; n = 3 
B:14:P1.9; n = 3  B:4:P1.12; n = 12  B:NT:P1.7; n = 21  C:4:P1.16; n = 1  Y:NT:P1.12; n = 1 
B:14:P1.NT; n = 36  B:4:P1.12,16; n = 1  B:NT:P1.7,16; n = 3  C:4:P1.2,5; n = 2  Y:NT:P1.14; n = 1 
B:15:P1.1,7; n = 2  B:4:P1.14; n = 34  B:NT:P1.9; n = 42  C:4:P1.4; n = 13  Y:NT:P1.15; n = 11 
B:15:P1.10; n = 14  B:4:P1.14,15; n = 4  B:NT:P1.NT; n = 123  C:4:P1.4,15; n = 1  Y:NT:P1.6; n = 2 
B:15:P1.12; n = 1  B:4:P1.15; n = 129  C:1:P1.1; n = 2  C:4:P1.4,7; n = 1  Y:NT:P1.7; n = 1 
B:15:P1.14; n = 2  B:4:P1.16; n = 63  C:1:P1.16; n = 4  C:4:P1.5; n = 2  Z:NT:P1.16; n = 2 
B:15:P1.15; n = 11  B:4:P1.2; n = 9  C:1:P1.5; n = 1  C:4:P1.6; n = 1  Z:NT:P1.NT; n = 1 
B:15:P1.16; n = 27  B:4:P1.2,5; n = 52  C:1:P1.7; n = 1  C:4:P1.7; n = 1  Ng:14:P1.2,5; n = 1 
B:15:P1.2,5; n = 5  B:4:P1.2,7; n = 1  C:1:P1.NT; n = 7  C:4:P1.9; n = 2  Ng:14:P1.NT; n = 1 
B:15:P1.4; n = 77  B:4:P1.4; n = 1376  C:14:P1.12; n = 2  C:4:P1.NT; n = 6  Ng:15:P1.7,16; n = 1 
B:15:P1.4,7; n = 2  B:4:P1.4,15; n = 4  C:14:P1.2,5; n = 3  C:NT:P1.1; n = 3  Ng:2b:P1.10; n = 1 
B:15:P1.5; n = 12  B:4:P1.4,7; n = 17  C:14:P1.4; n = 1  C:NT:P1.1,7; n = 4  Ng:4:P1.10; n = 1 
B:15:P1.6; n = 8  B:4:P1.5; n = 25  C:14:P1.7,16; n = 1  C:NT:P1.1,7; n = 4  Ng:4:P1.4; n = 1 
B:15:P1.7; n = 53  B:4:P1.6; n = 29  C:14:P1.NT; n = 1  C:NT:P1.10; n = 4  Ng:NT:P1.1,7; n = 1 
B:15:P1.7,14; n = 1  B:4:P1.7; n = 47  C:15:P1.7; n = 1  C:NT:P1.12; n = 1  Ng:NT:P1.2,5; n = 1 
B:15:P1.7,15; n = 2  B:4:P1.7,10; n = 2  C:15:P1.7,16; n = 2  C:NT:P1.14; n = 1  29^{E}16:P1.2,5; n = 2 
B:15:P1.7,16; n = 109  B:4:P1.7,14; n = 1  C:15:P1.NT; n = 1  C:NT:P1.15; n = 1  29^{E}NT:P1.2,5; n = 1 
B:15:P1.9; n = 30  B:4:P1.7,15; n = 2  C:16:P1.1,7; n = 4  C:NT:P1.16; n = 1  29^{E}NT:P1.NT; n = 1 
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