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Volume 10, Number 9—September 2004

Research

Space-Time Cluster Analysis of Invasive Meningococcal Disease

Christian J.P.A. Hoebe*Comments to Author , Hester de Melker†, Lodewijk Spanjaard‡, Jacob Dankert‡1, and Nico Nagelkerke†
Author affiliations: *Eastern South Limburg Municipal Public Health Service, Heerlen, the Netherlands; †National Institute of Public Health and the Environment, Bilthoven, the Netherlands; ‡Netherlands Reference Laboratory for Bacterial Meningitis, Amsterdam, the Netherlands; 1Deceased 24 January 2004.

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A:4:P1.NT; n = 1 B:15:P1.NT; n = 33 B:4:P1.7,16; n = 4 C:16:P1.16; n = 1 C:NT:P1.2; n = 1
A:NT:P1.16; n = 4 B:16:P1.1; n = 2 B:4:P1.7,9; n = 1 C:16:P1.2; n = 11 C:NT:P1.2,5; n = 5
B:1:P1.1,7; n = 1 B:16:P1.14; n = 10 B:4:P1.9; n = 36 C:16:P1.2,5; n = 18 C:NT:P1.5; n = 20
B:1:P1.10; n = 1 B:16:P1.16; n = 8 B:4:P1.NT; n = 455 C:16:P1.NT; n = 5 C:NT:P1.5,10; n = 1
B:1:P1.12; n = 2 B:16:P1.2; n = 9 B:4,14:P1.14; n = 2 C:2a:P1.1;n = 1 C:NT:P1.6; n = 7
B:1:P1.14; n = 25 B:16:P1.2,5; n = 22 B:4,14:P1.16; n = 4 C:2a:P1.16; n = 8 C:NT:P1.7; n = 7
B:1:P1.15; n = 2 B:16:P1.2,7; n = 1 B:4,14:P1.4; n = 4 C:2a:P1.2; n = 42 C:NT:P1.7,9; n = 1
B:1:P1.16; n = 92 B:16:P1.4; n = 1 B:4,14:P1.5; n = 1 C:2a:P1.2,5; n = 164 C:NT:P1.9; n = 1
B:1:P1.4; n = 87 B:16:P1.5; n = 3 B:4,14:P1.9; n = 1 C:2a:P1.4; n = 4 C:NT:P1.NT; n = 9
B:1:P1.4,14; n = 1 B:16:P1.6; n = 2 B:4,14:P1.NT; n = 4 C:2a:P1.5; n = 163 W135:2a:P1.2,5; n = 16
B:1:P1.5; n = 15 B:16:P1.7; n = 3 B:4,15:P1.10; n = 1 C:2a:P1.6; n = 2 W135:4,15:P1.16; n = 1
B:1:P1.5,9; n = 1 B:16:P1.7,16; n = 1 B:4,15:P1.4; n = 2 C:2a:P1.7,15; n = 1 W135:NT:P1.1,7; n = 5
B:1:P1.6; n = 3 B:16:P1.NT; n = 9 B:4,15:P1.7; n = 1 C:2a:P1.9; n = 3 W135:NT:P1.2; n = 1
B:1:P1.7,16; n = 7 B:2a:P1.1; n = 1 B:4,15:P1.NT; n = 1 C:2a:P1.NT; n = 44 W135:NT:P1.2,5; n = 2
B:1:P1.9; n = 1 B:2a:P1.16; n = 1 B:4,16:P1.4; n = 1 C:2a,1:P1.16; n = 1 W135:NT:P1.5; n = 5
B:1:P1.9,12; n = 1 B:2a:P1.2; n = 1 B:4,16:P1.7; n = 2 C:2b:P1.1; n = 1 W135:NT:P1.6; n = 25
B:1:P1.NT; n = 61 B:2a:P1.2,5; n = 2 B:NT:P1.1; n = 3 C:2b:P1.1,7; n = 3 W135:NT:P1.NT; n = 4
B:14:P1.1; n = 2 B:2a:P1.4,5; n = 1 B:NT:P1.1,7; n = 10 C:2b:P1.10; n = 9 X:4:P1.16; n = 3
B:14:P1.1,7; n = 1 B:2a:P1.7,16; n = 1 B:NT:P1.10; n = 23 C:2b:P1.14; n = 2 X:4:P1.7; n = 1
B:14:P1.12; n = 9 B:2a:P1.NT; n = 3 B:NT:P1.10,14; n = 1 C:2b:P1.15; n = 1 X:4:P1.7,15; n = 1
B:14:P1.14; n = 2 B:2a,1:P1.2,5; n = 1 B:NT:P1.12; n = 9 C:2b:P1.16; n = 1 X:4:P1.NT; n = 1
B:14:P1.15; n = 17 B:2a,1:P1.NT; n = 1 B:NT:P1.14; n = 23 C:2b:P1.2; n = 5 X:NT:P1.16; n = 1
B:14:P1.16; n = 1 B:2b:P1.1,7; n = 1 B:NT:P1.15; n = 39 C:2b:P1.2,12; n = 2 Y:14:P1.14; n = 1
B:14:P1.2,5; n = 3 B:2b:P1.10; n = 34 B:NT:P1.16; n = 20 C:2b:P1.2,5; n = 66 Y:14:P1.2,5; n = 2
B:14:P1.4; n = 85 B:2b:P1.12; n = 1 B:NT:P1.2; n = 5 C:2b:P1.4; n = 1 Y:14:P1.5; n = 1
B:14:P1.4,15; n = 1 B:2b:P1.15; n = 1 B:NT:P1.2,5; n = 20 C:2b:P1.5; n = 2 Y:14:P1.7,14; n = 1
B:14:P1.4,7; n = 1 B:2b:P1.2,5; n = 8 B:NT:P1.2,7; n = 1 C:2b:P1.NT; n = 8 Y:14:P1.NT; n = 4
B:14:P1.5; n = 4 B:2b:P1.7; n = 1 B:NT:P1.4; n = 102 C:4:P1.1; n = 16 Y:15:P1.16; n = 1
B:14:P1.5,10; n = 1 B:2b:P1.NT; n = 9 B:NT:P1.4,12; n = 2 C:4:P1.1,7; n = 1 Y:15:P1.5; n = 1
B:14:P1.6; n = 1 B:4:P1.1; n = 4 B:NT:P1.4,7; n = 2 C:4:P1.10; n = 5 Y:4:P1.5; n = 7
B:14:P1.7; n = 1 B:4:P1.1,7; n = 15 B:NT:P1.5; n = 8 C:4:P1.14; n = 1 Y:4:P1.NT; n = 1
B:14:P1.7,16; n = 1 B:4:P1.10; n = 205 B:NT:P1.6; n = 30 C:4:P1.15; n = 4 Y:4,14:P1.5; n = 3
B:14:P1.9; n = 3 B:4:P1.12; n = 12 B:NT:P1.7; n = 21 C:4:P1.16; n = 1 Y:NT:P1.12; n = 1
B:14:P1.NT; n = 36 B:4:P1.12,16; n = 1 B:NT:P1.7,16; n = 3 C:4:P1.2,5; n = 2 Y:NT:P1.14; n = 1
B:15:P1.1,7; n = 2 B:4:P1.14; n = 34 B:NT:P1.9; n = 42 C:4:P1.4; n = 13 Y:NT:P1.15; n = 11
B:15:P1.10; n = 14 B:4:P1.14,15; n = 4 B:NT:P1.NT; n = 123 C:4:P1.4,15; n = 1 Y:NT:P1.6; n = 2
B:15:P1.12; n = 1 B:4:P1.15; n = 129 C:1:P1.1; n = 2 C:4:P1.4,7; n = 1 Y:NT:P1.7; n = 1
B:15:P1.14; n = 2 B:4:P1.16; n = 63 C:1:P1.16; n = 4 C:4:P1.5; n = 2 Z:NT:P1.16; n = 2
B:15:P1.15; n = 11 B:4:P1.2; n = 9 C:1:P1.5; n = 1 C:4:P1.6; n = 1 Z:NT:P1.NT; n = 1
B:15:P1.16; n = 27 B:4:P1.2,5; n = 52 C:1:P1.7; n = 1 C:4:P1.7; n = 1 Ng:14:P1.2,5; n = 1
B:15:P1.2,5; n = 5 B:4:P1.2,7; n = 1 C:1:P1.NT; n = 7 C:4:P1.9; n = 2 Ng:14:P1.NT; n = 1
B:15:P1.4; n = 77 B:4:P1.4; n = 1376 C:14:P1.12; n = 2 C:4:P1.NT; n = 6 Ng:15:P1.7,16; n = 1
B:15:P1.4,7; n = 2 B:4:P1.4,15; n = 4 C:14:P1.2,5; n = 3 C:NT:P1.1; n = 3 Ng:2b:P1.10; n = 1
B:15:P1.5; n = 12 B:4:P1.4,7; n = 17 C:14:P1.4; n = 1 C:NT:P1.1,7; n = 4 Ng:4:P1.10; n = 1
B:15:P1.6; n = 8 B:4:P1.5; n = 25 C:14:P1.7,16; n = 1 C:NT:P1.1,7; n = 4 Ng:4:P1.4; n = 1
B:15:P1.7; n = 53 B:4:P1.6; n = 29 C:14:P1.NT; n = 1 C:NT:P1.10; n = 4 Ng:NT:P1.1,7; n = 1
B:15:P1.7,14; n = 1 B:4:P1.7; n = 47 C:15:P1.7; n = 1 C:NT:P1.12; n = 1 Ng:NT:P1.2,5; n = 1
B:15:P1.7,15; n = 2 B:4:P1.7,10; n = 2 C:15:P1.7,16; n = 2 C:NT:P1.14; n = 1 29E16:P1.2,5; n = 2
B:15:P1.7,16; n = 109 B:4:P1.7,14; n = 1 C:15:P1.NT; n = 1 C:NT:P1.15; n = 1 29ENT:P1.2,5; n = 1
B:15:P1.9; n = 30 B:4:P1.7,15; n = 2 C:16:P1.1,7; n = 4 C:NT:P1.16; n = 1 29ENT:P1.NT; n = 1

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