Volume 11, Number 1—January 2005
Research
Dengue and Dengue Hemorrhagic Fever, Brazil, 1981–2002
João Bosco Siqueira*†
, Celina Maria Turchi Martelli†, Giovanini Evelim Coelho*, Ana Cristina da Rocha Simplício*, and Douglas L. Hatch*‡
, Celina Maria Turchi Martelli†, Giovanini Evelim Coelho*, Ana Cristina da Rocha Simplício*, and Douglas L. Hatch*‡Table 1
Chronology of major dengue-related events in Brazil, 1981–2002
| Period/y | Event |
|---|---|
| 1981–1993: Epidemics waves in localized areas | |
| 1981 | Restricted outbreak (DENV1* and DENV4†) in Northwest Brazil (Roraima State) |
| 1986 | Introduction of DENV1 (Rio de Janeiro State) |
| 1990 | Introduction of DENV2‡ (Rio de Janeiro State) and first confirmed cases of DHF |
| 1994–2002: Epidemic and endemic virus circulation countrywide | |
| 1994–1999 | Dispersion of Aedes aegypti nationwide |
| 1998 | Widespread outbreaks in 16 states (>534,000 reported cases) |
| 2000 | Introduction of DENV3§ (Rio de Janeiro State) |
| 2002 | Large outbreaks in 19 states (>794,000 reported cases) Deaths due to dengue hemorrhagic fever exceed deaths from malaria |
*Dengue virus serotype 1.
†Dengue virus serotype 4.
‡Dengue virus serotype 2.
§Dengue virus serotype 3.
