Volume 11, Number 1—January 2005
Dispatch
Mycobacterium tuberculosis Beijing Genotype, Northern Malawi
Judith R. Glynn*
, Amelia C. Crampin*†, Hamidou Traore*, Malcolm D. Yates‡, Frank D. Mwaungulu†, Bagrey M. Ngwira†, Steven D. Chaguluka†, Donex T. Mwafulirwa†, Sian Floyd*, Caroline Murphy‡, Francis A. Drobniewski‡, and Paul E.M. Fine*
, Amelia C. Crampin*†, Hamidou Traore*, Malcolm D. Yates‡, Frank D. Mwaungulu†, Bagrey M. Ngwira†, Steven D. Chaguluka†, Donex T. Mwafulirwa†, Sian Floyd*, Caroline Murphy‡, Francis A. Drobniewski‡, and Paul E.M. Fine*Table
Comparison of persons with Beijing and non-Beijing genotype Mycobacterium tuberculosis
| Characteristic | Beijing genotype, n (%) | Other genotypes, n (%) | p value |
|---|---|---|---|
| Sex | 0.001 | ||
| Male | 10 (22.7) | 472 (47.9) | |
| Female | 34 (77.3) | 513 (52.1) | |
| Age group | 0.3 | ||
| <15 | 2 (4.6) | 16 (1.6) | |
| 15–29 | 17 (38.6) | 306 (31.1) | |
| 30–44 | 16 (36.4) | 423 (42.9) | |
| >45 | 9 (20.5) | 240 (24.4) | |
| Born in Malawi | 0.08 | ||
| Yes | 38 (90.5) | 747 (79.2) | |
| No | 4 (9.5) | 196 (20.8) | |
| Moved in last 5 y | 0.8 | ||
| No move | 16 (40.0) | 343 (41.2) | |
| Within district | 10 (25.0) | 188 (22.6) | |
| Outside district | 9 (22.5) | 226 (27.1) | |
| Outside country | 5 (12.5) | 76 (9.1) | |
| HIV status | 0.4 | ||
| Positive | 15 (57.7) | 396 (65.6) | |
| Negative | 11 (42.3) | 208 (34.4) | |
| Previous tuberculosis (TB) | 0.9 | ||
| Yes | 3 (6.8) | 74 (7.6) | |
| No | 41 (93.2) | 904 (92.4) | |
| BCG scar | 0.7 | ||
| Yes | 23 (74.2) | 486 (69.7) | |
| No | 6 (19.4) | 176 (25.3) | |
| Doubtful | 2 (6.5) | 35 (5.0) | |
| Contact with TB patient in district | 0.6 | ||
| Yes | 22 (50.0) | 453 (46.0) | |
| No | 22 (50.0) | 532 (54.0) | |
| Type of TB | 0.4 | ||
| Smear-positive pulmonary | 33 (75.0) | 711 (72.2) | |
| Smear-negative pulmonary | 10 (22.7) | 202 (20.5) | |
| Extrapulmonary | 1 (2.3) | 72 (7.3) | |
| Drug resistance | 0.2 | ||
| Sensitive | 44 (100) | 920 (93.9) | |
| Resistant isoniazid only | 0 | 38 (3.9) | |
| Resistant isoniazid plus | 0 | 22 (2.2) | |
| Died during treatment | 0.7 | ||
| Yes | 13 (32.5) | 224 (29.6) | |
| No | 27 (67.5) | 532 (70.4) |
