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Volume 11, Number 6—June 2005

Research

Emergence and Spread of Streptococcus pneumoniae with erm(B) and mef(A) Resistance

David J. Farrell*Comments to Author , Stephen G. Jenkins†, Steven D. Brown‡, Manish Patel§, Bruce S. Lavin§, and Keith P. Klugman¶#
Author affiliations: *G.R. Micro Ltd, London, United Kingdom; †Mount Sinai School of Medicine, New York, New York, USA; ‡Clinical Microbiology Institute, Wilsonville, Oregon, USA; §sanofi-aventis, Bridgewater, New Jersey, USA; ¶Emory University, Atlanta, Georgia, USA; #University of the Witwatersrand, Johannesburg, South Africa

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Table 6

Lineage by country of 366 dual erm(B)+mef(A) erythromycin-resistant Streptococcus pneumoniae isolates collected during the PROTEKT global study (1999–2003)

Country No. isolates Clonal complex
CC 271 CC 242 CC 81 None*
Australia 6 6
Brazil 2 2
Canada 4 4
China 13 12 1
France 3 1 2
Germany 1 1
Hong Kong 2 2
Hungary 2 2
Italy 2 2
Japan 44 12 16 1 15†
Mexico 6 4 2
South Africa 129 116 9 2 2
South Korea 111 102 6 3
Taiwan 5 3 2
United Kingdom 1 1
United States 35 35
Total, n (%) 366 (100) 305 (83.3) 25 (6.8) 9 (2.5) 27 (7.4)

*No clonal lineage found except for 2 isolates (ST 1467) and 1 isolate (ST 1452), which were clonally related (CC 1467).
†8 isolates were clonally related (ST 1426).

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