Volume 13, Number 1—January 2007
Dispatch
Ophthalmic Surgery in Prion Diseases
Tsuyoshi Hamaguchi*1, Moeko Noguchi-Shinohara*, Yosikazu Nakamura†2, Takeshi Sato‡2, Tetsuyuki Kitamoto§2, Hidehiro Mizusawa¶2, and Masahito Yamada*2
Table 1
Characteristics of sCJD patients and ophthalmic surgery*
| Patient no. | Sex/age, y† | Disease duration, mo‡ | Symptom at sCJD onset | Ophthalmic disease | Interval, mo§ | Visual symptoms after surgery | Reused instruments | Cleaning method |
|---|---|---|---|---|---|---|---|---|
| 1 | M/81 | 8 | Visual | Cataract | 4 | NA | NA | NA |
| 2 | M/61 | 15 | Dementia | Cataract | 0 | Improved | Yes | Autoclave (135°C for 9 min) |
| 3 | F/64 | 20 | Visual | Cataract | 14 | Not changed | Yes | EOG |
| 4 | F/59 | 3 | Dementia | Detached retina | –1 | Improved | Yes | EOG |
| 5 | F/57 | 10 | Dementia | Cataract | 10 | NA | NA | NA |
| 6 | F/79 | 5 | Dementia | Cataract | –1 | Improved | Yes | EOG |
| 7 | M/74 | 16 | Visual | Cataract | 3 | Improved | Yes | Autoclave (132°C for 10 min), EOG |
| 8 | F/63 | 5 | Visual | Cataract | 1 | Deteriorated | Yes | Autoclave (132°C for 10 min) |
| 9 | M/79 | 6 | Gait disturbance | Cataract | 2 | Not changed | Yes | Autoclave (121°C for 60 min) |
| 10 | F/66 | 3 | Dementia | Cataract | 1 | NA | NA | NA |
*sCJD, sporadic Creutzfeldt-Jakob disease; visual, visual impairment; NA, not available; EOG, ethylene oxide gas.
†At sCJD onset.
‡Disease duration, the duration from onset to akinetic mutism state or death if the patients never displayed akinetic mutism.
§Between surgery and sCJD symptoms.
