Skip directly to local search Skip directly to A to Z list Skip directly to navigation Skip directly to site content Skip directly to page options
CDC Home

Volume 13, Number 12—December 2007

Research

Phenotypic Similarity of Transmissible Mink Encephalopathy in Cattle and L-type Bovine Spongiform Encephalopathy in a Mouse Model

Thierry G.M. Baron*Comments to Author , Anna Bencsik*, Anne-Gaëlle Biacabe*, Eric Morignat*, and Richard A. Bessen†
Author affiliations: *Agence Française de Sécurité Sanitaire des Aliments–Lyon, Lyon, France; †Montana State University, Bozeman, Montana, USA;

Main Article

Figure 3

Western blot of protease-resistant prion protein from TgOvPrP4 mice after proteinase K digestion and immunodetection with anti-PrP Sha31 antibody. A) First passage of typical bovine spongiform encephalopathy (BSE) (lanes 2, 4, and 6) and L-type BSE (lanes 3, 5, and 7). B) First passage of TME in cattle (lanes 2, 4, and 6) and L-type (lanes 3, 5, and 7). C) Second passage of TME in cattle (lanes 2, 4, and 6) and L-type BSE (lanes 3, 5, and 7). Each lane shows PrPres from a distinct individual mouse from each experimental group. Bars to the left of the panel indicate the 29.0- and 20.1-kDa marker positions. Lane 1, PrPres control from a scrapie-infected TgOvPrP4 mouse (C506M3 strain).

Figure 3. Western blot of protease-resistant prion protein from TgOvPrP4 mice after proteinase K digestion and immunodetection with anti-PrP Sha31 antibody. A) First passage of typical bovine spongiform encephalopathy (BSE) (lanes 2, 4, and 6) and L-type BSE (lanes 3, 5, and 7). B) First passage of TME in cattle (lanes 2, 4, and 6) and L-type (lanes 3, 5, and 7). C) Second passage of TME in cattle (lanes 2, 4, and 6) and L-type BSE (lanes 3, 5, and 7). Each lane shows PrPres from a distinct individual mouse from each experimental group. Bars to the left of the panel indicate the 29.0- and 20.1-kDa marker positions. Lane 1, PrPres control from a scrapie-infected TgOvPrP4 mouse (C506M3 strain).

Main Article

Top of Page

 

Past Issues

Select a Past Issue:

World Malaria Day - April 25, 2014 - Invest in the future, defeat malaria

20th Anniversary - National Infant Immunization Week - Immunization. Power to Protect.

Art in Science - Selections from Emerging Infectious Diseases
Now available for order



CDC 24/7 – Saving Lives, Protecting People, Saving Money. Learn More About How CDC Works For You…

USA.gov: The U.S. Government's Official Web PortalDepartment of Health and Human Services
Centers for Disease Control and Prevention   1600 Clifton Rd. Atlanta, GA 30333, USA
800-CDC-INFO (800-232-4636) TTY: (888) 232-6348 - Contact CDC–INFO