Emerging Infectious Disease ISSN: 1080-6059

Norovirus in Captive Lion Cub (Panthera leo)

Vito Martella*

, Marco Campolo*, Eleonora Lorusso*, Paolo Cavicchio†, Michele Camero*, Anna L. Bellacicco*, Nicola Decaro*, Gabriella Elia*, Grazia Greco*, Marialaura Corrente*, Costantina Desario*, Serenella Arista‡, Krisztián Banyai§, Marion Koopmans¶, and Canio Buonavoglia*

Author affiliations: *University of Bari, Valenzano, Bari, Italy; †Giardino Zoologico di Pistoia, Pistoia, Italy; ‡University of Palermo, Palermo, Italy; §Baranya County Institute of State Public Health Service, Pécs, Hungary; ¶National Institute of Public Health and the Environment, Bilthoven, the Netherlands;

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Figure 1

Genome organization of the lion norovirus (NoV) 387/06. A nucleotide identity plot of the genome of the lion NoV (from the 3′ end of open reading frame [ORF] 1 to the poly-A tail) was compared with the human genogroup IV.1 NoV, Fort Lauderdale/560/98/US (AF414426). The sequences were analyzed with Simplot software (http://sray.med.som.jhmi.edu/scroftware/simplot) by using a window size of 200 and step size of 20 with gap strip off and J-C correction on. The ORF1–ORF2 junction region is shown with the starting and stopping codons ATG and TGA underlined. The highly conserved domain S and the highly variable domains P1 and P2 of the capsid protein are also indicated.

Figure 1. Genome organization of the lion norovirus (NoV) 387/06. A nucleotide identity plot of the genome of the lion NoV (from the 3′ end of open reading frame [ORF] 1 to the poly-A tail) was compared with the human genogroup IV.1 NoV, Fort Lauderdale/560/98/US (AF414426). The sequences were analyzed with Simplot software (http://sray.med.som.jhmi.edu/scroftware/simplot) by using a window size of 200 and step size of 20 with gap strip off and J-C correction on. The ORF1–ORF2 junction region is shown with the starting and stopping codons ATG and TGA underlined. The highly conserved domain S and the highly variable domains P1 and P2 of the capsid protein are also indicated.

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