Outbreak of Antiviral Drug–Resistant Influenza A in Long-Term Care Facility, Illinois, USA, 2008
Nila J. Dharan1, Monica Patton1, Alicia M. Siston2, Julie Morita, Enrique Ramirez, Teresa R. Wallis, Varough Deyde, Larisa V. Gubareva, Alexander I. Klimov, Joseph S. Bresee, and Alicia M. Fry
Author affiliations: Centers for Disease Control and Prevention, Atlanta, Georgia, USA (N.J. Dharan, M. Patton, T.W. Wallis, V. Deyde, L.V. Gubareva, A.I. Klimov, J.S. Bresee, A.M. Fry); Chicago Department of Public Health, Chicago, Illinois, USA (A.M. Siston, J. Morita, E. Ramirez); 1Current affiliation: New York University School of Medicine, New York, New York, USA.; 2Current affiliation: Centers for Disease Control and Prevention, Atlanta, Georgia, USA.
Figure 2. Phylogenetic analysis of the hemagglutinin gene (HA1 portion) of influenza A viruses (H1N1) isolated during an influenza A outbreak in a long-term care facility, Illinois, USA, 2008. Viruses from buildings A and B shared nearly identical sequences. One of the viruses from building B was more similar in sequence to 1 virus from building A. However, this finding could reflect natural variance in circulating viruses. Red indicates outbreak viruses, boldface italics indicates vaccine strain for 2008–09, boldface indicates vaccine strain for 2007–08, and arrows indicate nucleotide differences in HA1 subunit. Scale bar indicates nucleotide substitutions per site.
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