Volume 15, Number 12—December 2009
Dispatch
Outbreak of Antiviral Drug–Resistant Influenza A in Long-Term Care Facility, Illinois, USA, 2008
Nila J. Dharan1, Monica Patton1, Alicia M. Siston2, Julie Morita, Enrique Ramirez, Teresa R. Wallis, Varough Deyde, Larisa V. Gubareva, Alexander I. Klimov, Joseph S. Bresee, and Alicia M. Fry
Table
Characteristics of 12 confirmed influenza case-patients in building A, long-term care facility, Illinois, USA, 2008*
| Characteristic | Influenza virus subtype |
|
|---|---|---|
| A (H1) (n = 9) | A (H3) (n = 3) | |
| Age, y, median (range) |
29 (14–47) |
32 (21–37) |
| Any underlying medical conditions | 9 (100) | 3 (100) |
| Neurologic disorders | 9 (100) | 3 (100) |
| Gastrointestinal disorders | 8 (89) | 3 (100) |
| Pulmonary disease |
2 (22) |
2 (67) |
| Fever >100.5°F |
9 (100) |
3 (100) |
| Cough |
7 (78) |
2 (67) |
| Desaturation | 4 (44) | 1 (33) |
| Lowest % oxygen saturation, median (range) | 88.5 (88–92) | 92 (NA) |
| Elevated or new oxygen requirement |
2 (22) |
0 |
| Difficulty breathing |
2 (22) |
1 (33) |
| Increased secretions |
3 (33) |
2 (67) |
| Increased respiratory rate |
3 (33) |
0 |
| Lethargy |
1 (11) |
0 |
| Distress |
3 (33) |
0 |
| Elevated level of care |
4 (44) |
1 (33) |
| Hospitalized† | 1 (11) | 0 |
| Length of stay, d |
1 |
NA |
| Clinical treatment | ||
| Antimicrobial drugs | 3 (33) | 0 |
| Antipyretics | 9 (100) | 3 (100) |
| Nebulizer (albuterol) |
3 (33) |
1 (33) |
| Received 2007–08 influenza vaccine |
8 (89) |
3 (100) |
| Died‡ | 1 (11) | 0 |
*All values are no. (%) case-patients except as indicated. NA, not applicable.
†One case-patient was hospitalized for parotitis to rule out infection with mumps and was discharged in stable condition after 1 day.
‡One case-patient who had a diagnosis of end-stage lung disease and a do not resuscitate/do not intubate directive died.
