Emerging Infectious Disease ISSN: 1080-6059

Bacterial Phenotype Variants in Group B Streptococcal Toxic Shock Syndrome1

Parham Sendi²

, Linda Johansson, Samira Dahesh, Nina M. Van Sorge, Jessica Darenberg, Mari Norgren, Jan Sjölin, Victor Nizet, and Anna Norrby-Teglund

Author affiliations: Karolinska Institutet, Stockholm, Sweden (P. Sendi, L. Johansson, A. Norrby-Teglund); Basel University Medical Clinic, Liestal, Switzerland (P. Sendi); University of California San Diego, La Jolla, California, USA (S. Dahesh, N.M. Van Sorge, V. Nizet); Swedish Institute for Infectious Disease Control, Stockholm (J. Darenberg); Umeå University, Umeå, Sweden (M. Norgren); Uppsala University, Uppsala, Sweden (J. Sjölin)

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Figure 2

A) Buoyant density analysis of the low hemolytic (LH) and high hemolytic (HH) strains, exhibiting lower and higher buoyant density, respectively. B) Quantification of group B streptococci sialic acids expressed as fmol N-acetylneuraminic acid/1,000 CFUs of the LH and HH phenotypes. Error bars indicate SEM. C C) Transmission electron microscopy of LH and HH phenotypic variants.

Figure 2. A) Buoyant density analysis of the low hemolytic (LH) and high hemolytic (HH) strains, exhibiting lower and higher buoyant density, respectively. B) Quantification of group B streptococci sialic acids expressed as fmol N-acetylneuraminic acid/1,000 CFUs of the LH and HH phenotypes. Error bars indicate SEM. C C) Transmission electron microscopy of LH and HH phenotypic variants.

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¹Part of this work was presented at Lancefield 2008 International Symposium on Streptococci and Streptococcal Diseases, Porto Heli, Greece, June 22–26, 2008.

²Current affiliation: Clinic for Infectious Diseases, University Hospital Bern, Bern, Switzerland.

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