Emerging Infectious Disease ISSN: 1080-6059

Epidemiologic Study of Vibrio vulnificus Infections by Using Variable Number Tandem Repeats

Yoav Y. Broza, Yael Danin-Poleg, Larisa Lerner, Lea Valinsky, Meir Broza, and Yechezkel Kashi

Author affiliations: Technion-Israel Institute of Technology, Haifa, Israel (Y.Y. Broza, Y. Danin-Poleg, Y. Kashi); Ministry of Health, Jerusalem, Israel (L. Lerner, L. Valinsky); University of Haifa, Oranim, Tivon, Israel (M. Broza)

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Figure 1

A) Genetic relationships based on simple-sequence repeat (SSR) variation data among 183 Vibrio vulnificus isolates including 135 new environmental, 22 new clinical, and 26 previously studied isolates. B) A subtree enlargement of panel A displaying a set of 65 V. vulnificus biotype 3 isolates. Similar clinical and environmental isolates, showing an epidemiologic connection, are indicated by arrows. The genetic-distance matrix was generated based on 212 polymorphic points (the sum of alleles across 12 SSR loci). Genetic relationships are based on unweighted pair group method with arithmetic mean cluster analysis of SSR variation using MEGA4 software (11). Scale bar represents genetic distance.

Figure 1. A) Genetic relationships based on simple-sequence repeat (SSR) variation data among 183 Vibrio vulnificus isolates including 135 new environmental, 22 new clinical, and 26 previously studied isolates. B) A subtree enlargement of panel A displaying a set of 65 V. vulnificus biotype 3 isolates. Similar clinical and environmental isolates, showing an epidemiologic connection, are indicated by arrows. The genetic-distance matrix was generated based on 212 polymorphic points (the sum of alleles across 12 SSR loci). Genetic relationships are based on unweighted pair group method with arithmetic mean cluster analysis of SSR variation using MEGA4 software (11). Scale bar represents genetic distance.

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