Volume 15, Number 8—August 2009
National Outbreak of Acanthamoeba Keratitis Associated with Use of a Contact Lens Solution, United States
|Contact lens wear|
|Did not use contact lenses||12 (11)|
|Used contact lenses||93 (89)|
|Soft lenses||82 (88)|
|Rigid lenses||10 (11)|
|Hybrid lenses||1 (1)|
|Contact lens solution use among contact users†|
|Did not use cleaning or disinfecting contact lens solution||6 (6)|
|Used any type of cleaning or disinfecting contact lens solution||87 (94)|
|Type of solution used§|
|Multipurpose solution||78 (90)|
|Hydrogen peroxide solution||6 (7)|
|Daily cleaner||11 (13)|
|Symptoms when treatment sought‡§|
|Sensitivity to light||76 (72)|
|Sensation of foreign body||71 (68)|
|Increased tearing||59 (56)|
|Blurred vision||57 (54)|
|Discharge from eye||20 (19)|
|Resolved with pharmacologic therapy||32 (38)|
|Currently receiving pharmacologic therapy||29 (34)|
|Corneal transplant performed||21 (25)|
|Corneal transplant planned||3 (4)|
|Most recent visual acuity with best correction in affected eye#|
*Median 29 y, range 12–76 y.
†During 1 month before illness onset; n = 93.
‡Not mutually exclusive.
§Median time from symptom onset to anti-Acanthamoeba therapy (n = 80) was 49 d (range 4–197 d).
¶At the time of treating ophthalmologist interview; n = 85.
#At the time of treating ophthalmologist interview; n = 70.
1Other members of the Acanthamoeba Keratitis Investigation Team: Stephanie P. Johnston, Alexandre DaSilva, Yvonne Qvarnstrom, Rama R. Sriram, E. Danielle Rentz, Leslie B. Hausman, Shannon K. Cosgrove, Brandy L. Peterson, Nicholas P. DiMeo, Rebecca C. Greco-Kone, Angela J. Deokar, Susan Brim, Aaron S. Kusano, David E. Cheek, Sharlene Persaud, Felicia Chow (Centers for Disease Control and Prevention [CDC]); Ingrid Trevino, (CDC and Illinois Department of Public Health, Springfield, IL, USA); Gita G. Mirchandani (CDC and Maryland Department of Health and Mental Hygiene, Baltimore, MD, USA); Emily J. Luckman (Maryland Department of Health and Mental Hygiene); Stacy M. Holzbauer (CDC and Minnesota Department of Health, St. Paul, MN, USA); Zack Moore (CDC and North Carolina Department of Health and Human Services, Raleigh, NC, USA); Adam J. Langer, Mary T. Glenshaw (CDC and New Jersey Department of Health and Human Services, Trenton, NJ, USA); Michael Cooper (CDC and Ohio Department of Health, Columbus, OH, USA); Tai-Ho Chen (CDC and Pennsylvania Department of Health, Harrisburg, PA, USA); Kira A. Christian (CDC and South Carolina Department of Health and Environmental Control, Columbia, SC, USA); L. Rand Carpenter (CDC and Tennessee Department of Health, Nashville, TN, USA); Marion A. Kainer (Tennessee Department of Health); John R. Su (CDC and Texas Department of Health, Austin, TX, USA); Ami S. Patel (CDC and Virginia Department of Health, Richmond, VA, USA); Aron J. Hall (CDC and West Virginia Department of Health and Human Resources, Charleston, WV, USA); Charlotte E. Joslin (University of Illinois at Chicago); Kirk R. Wilhelmus (Baylor College of Medicine)