MedscapeCME is pleased to provide online continuing medical education (Medscape CME) for this journal article, allowing clinicians the opportunity to earn CME credit. This activity has been planned and implemented in accordance with the Essential Areas and policies of the Accreditation Council for Continuing Medical Education through the joint sponsorship of MedscapeCME and Emerging Infectious Diseases. MedscapeCME is accredited by the Accreditation Council for Continuing Medical Education (ACCME) to provide continuing medical education for physicians. MedscapeCME designates this educational activity for a maximum of 0.5 AMA PRA Category 1 Credits™. Physicians should only claim credit commensurate with the extent of their participation in the activity. All other clinicians completing this activity will be issued a certificate of participation. To participate in this journal CME activity: (1) review the learning objectives and author disclosures; (2) study the education content; (3) take the post-test and/or complete the evaluation at http://www.medscape.com/cme/eid; (4) view/print certificate.

Upon completion of this activity, participants will be able to:

Describe the incidence and etiology of Acanthamoeba keratitis (AK) infection in the United States

Identify the demographic and clinical characteristics of patients who acquired AK

Identify the risk factors for AK among contact lens users.

Carol Snarey, Copyeditor, Emerging Infectious Diseases. Disclosure: Carol Snarey has disclosed no relevant financial relationships.

Désirée Lie, MD, MSEd, Clinical Professor, Family Medicine, University of California, Orange; Director, Division of Faculty Development, UCI Medical Center, Orange, California. Disclosure: Désirée Lie, MD, MSEd, has disclosed no relevant financial relationships.

Disclosures: Jennifer R. Verani, MD, MPH; Suchita A. Lorick, DO, MPH; Jonathan S. Yoder, MPH, MSW; Michael J. Beach, PhD; Christopher R. Braden, MD; Jacquelin M. Roberts, MS; Craig S. Conover, MD; Sue Chen, MPH; Kateesha A. McConnell, MPH; Douglas C. Chang, MD; Benjamin J. Park, MD; Dan B. Jones, MD; Govinda S. Visvesvara, PhD; and Sharon L. Roy, MD, MPH, have disclosed no relevant financial relationships.