Volume 15, Number 9—September 2009
Research
Predicting Phenotype and Emerging Strains among Chlamydia trachomatis Infections
Deborah Dean
, William J. Bruno, Raymond Wan, João P. Gomes, Stéphanie Devignot, Tigist Mehari, Henry J.C. de Vries, Servaas A. Morré, Garry Myers, Timothy D. Read, and Brian G. Spratt
, William J. Bruno, Raymond Wan, João P. Gomes, Stéphanie Devignot, Tigist Mehari, Henry J.C. de Vries, Servaas A. Morré, Garry Myers, Timothy D. Read, and Brian G. SprattTable 3
Allele frequencies by geographic region by locus
| Gene locus | No. alleles | Allele frequency, no. (%)* |
Classification index p value | |||||
|---|---|---|---|---|---|---|---|---|
| Africa (n = 11) | Northern Europe (n = 14) | Southern Europe (n = 10) | Asia (n = 13) | North America (n = 33) | South America (n = 6) | |||
| glyA |
7 |
3 (90.9)
6 (9.1) |
1 (7.1)
3 (42.9)
4 (7.1)
5 (14.3)
6 (28.6) |
3 (60)
6 (40) |
3 (30.8)
6 (7.7)
7 (61.5) |
1 (15.1)
2 (3.0)
3 (54.6)
6 (27.3) |
3 (33.3)
6 (66.7) |
<0.001 |
| mdhC |
4 |
3 (90.9)
4 (9.1) |
1 (7.1)
2 (14.3)
3 (64.3)
4 (14.3) |
3 (80)
4 (20) |
3 (100) |
1 (18.2)
3 (72.7)
4 (9.1) |
3 (50.0)
4 (50.0) |
<0.001 |
| pdhA |
7 |
1 (9.1)
3 (90.9) |
2 (7.1)
3 (92.9) |
3 (60)
4 (30)
7 (10) |
3 (100) |
3 (94.0)
5 (3.0)
6 (3.0) |
3 (100.0) |
<0.001 |
| yhbG |
8 |
2 (9.1)
6 (90.9) |
2 (28.6)
3 (7.1)
6 (42.7)
8 (21.4) |
2 (40)
6 (50)
7 (10) |
1 (7.7)
4 (7.7)
5 (7.7)
6 (76.9) |
2 (21.2)
3 (3.0)
5 (3.0)
6 (57.6)
8 (15.2) |
2 (66.7)
6 (33.3) |
<0.001 |
| pykF |
7 |
3 (81.8)
6 (9.1)
7 (8.1) |
1 (12.5)
6 (50)
7 (37.5) |
6 (60)
7 (40) |
3 (92.3)
7 (7.7) |
1 (18.2)
2 (9.1)
4 (3.0)
5 (3.0)
6 (39.4)
7 (27.3) |
6 (33.3)
7 (66.7) |
<0.001 |
| lysS |
8 |
4 (15.2)
5 (72.7)
7 (9.1) |
1 (14.3)
4 (78.6)
8 (7.1) |
4 (70)
8 (30) |
4 (7.7)
5 (30.8)
6 (61.5) |
1 (3.0)
3 (3.0)
4 (75.8)
8 (18.2) |
2 (16.7)
4 (66.7)
8 (16.7) |
<0.001 |
| leuS |
11 |
2 (9,1)
3 (9.1)
9 (81.8) |
3 (57.1)
6 (21.4)
11(21.4) |
3 (80)
4 (10)
5 (10) |
2 (7.7)
7 (84.6)
10 (7.7) |
1 (3.0)
3 (48.5)
8 (30.3)
9 (3.0)
11 (15.2) |
3 (100.0) |
<0.001 |
| Total no. alleles | 52 | 17 | 24 | 17 | 17 | 31 | 13 | |
*Numbers are arranged vertically for each locus to represent the individual alleles (e.g., glyA, alleles are assigned 1, 2, 3, 4, 5, 6 and 7 because there are 7 alleles for this locus). Alleles marked in boldface are specific for a single geographic region. n values indicate number of samples.
