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Volume 16, Number 10—October 2010

Dispatch

Severe Plasmodium vivax Malaria, Brazilian Amazon

Márcia A. Alexandre, Cynthia O. Ferreira, André M. Siqueira, Belisa L. Magalhães, Maria Paula G. Mourão, Marcus V. LacerdaComments to Author , and Maria das Graças C. Alecrim
Author affiliations: Author affiliations: Fundação de Medicina Tropical do Amazonas, Manaus, Brazil (M.A. Alexandre, C.O. Ferreira, M.P.G. Mourão, M.V. Lacerda); Universidade do Estado do Amazonas, Manaus (M.A. Alexandre, A.M. Siqueira, B.L. Magalhães, M.P.G. Mourão, M.V. Lacerda, M.G.C. Alecrim); Centro Universitário Nilton Lins, Manaus (M.A. Alexandre, A.M. Siqueira, M.P.G. Mourão, M.V. Lacerda, M.G.C. Alecrim)

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Table 2

Laboratory characteristics of 17 hospitalized patients who had parasitologic and molecular diagnosis of Plasmodium vivax infection, Manaus, Brazil, 2001–2002*

Patient no. No. asexual parasites/mm3 Hemoglobin, g/dL Total leukocyte count, cells/mm3 Thrombocytes, cells/mm3 Serum creatinine, mg/dL Serum bilirubin, total/conjugated, mg/dL Serum AST, IU/L Serum ALT, IU/L
1 7,566 3.6 9,700 97,000 0.5 1.1/0.4 50 30
2 28,847 4.5 9,100 30,000 0.6 1.3/0.5 40 34
3 1,100 9.5 5,500 143,000 0.4 6.6/5.6 760 1,233
4 21,406 14.6 13,900 33,000 3.0 2.58/1.16 113 108
5 1,862 3.1 19,000 99,000 0.7 1.1/0.8 23 56
6 1,206 11.5 6,700 27,000 1.2 13.8/10.6 76 60
7 2,695 12.4 4,900 76,000 3.7 1.3/0.5 33 33
8 2,055 3.8 13,700 106,000 0.6 4.3/0.73 190 37
9 3,844 4.5 6,200 171,000 0.3 1.36/0.21 58 25
10 680 9.6 13,600 275,000 0.1 6.4/4.8 72 50
11 5,452 6.5 4,700 107,000 1.7 2.5/1.6 57 56
12 5,047 11.5 4,900 35,000 0.9 6.3/5.1 49 34
13 11,954 9.4 8,600 48,000 1.0 5.4/5.2 45 43
14 9,360 12.0 5,200 27,000 1.2 9.2/7.1 57 53
15 4,524 8.8 5,800 29,000 1.0 5.6/4.8 33 30
16 5,160 10.7 6,300 36,000 2.3 7.8/6.5 35 70
17 24,550 10.3 5,000 24,000 1.4 7.1/4.6 39 55

*WHO, World Health Organization; AST, aspartate aminotransferase; ALT, alanine aminotransferase.

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