Volume 16, Number 11—November 2010
Dispatch
Experimental Pandemic (H1N1) 2009 Virus Infection of Cats
Judith M.A. van den Brand, Koert J. Stittelaar, Geert van Amerongen, Marco W.G. van de Bildt, Lonneke M.E. Leijten, Thijs Kuiken, and Albert D.M.E. Osterhaus
Table
Test results for 8 cats intratracheally infected with pandemic (H1N1) 2009 virus*
| Tissue source | No. positive |
||||
|---|---|---|---|---|---|
| IHC analysis |
Virus isolation† |
||||
| 4 dpi | 7 dpi | 4 dpi | 7 dpi | ||
| Respiratory | |||||
| Lung | 4 | 3 | 4 | 1 | |
| Bronchus | 2 | 0 | 4 | 0 | |
| Trachea | 0 | 0 | 4 | 1 | |
| Nasal turbinates |
0 |
0 |
2 |
0 |
|
| Extrarespiratory | |||||
| Liver | 0 | 0 | 0 | 1 | |
| Intestine | 0 | 0 | 1 | 1 | |
| Olfactory bulb | 0 | 0 | 0 | 1 | |
| Brain | 0 | 0 | 0 | 1 | |
| Spleen | 0 | 0 | 1 | 0 | |
| Tonsil | 0 | 0 | 2 | 0 | |
| Adrenal gland | 0 | 0 | 0 | 2 | |
| Nictitating membrane | 0 | 0 | 0 | 2 | |
*Four cats were examined on each day. IHC, immunohistochemical; dpi, days postinfection.
†No virus was isolated from tracheobronchial lymph node, pancreas, heart, or kidney of any cats.
