Volume 16, Number 3—March 2010
Research
Vaccine Preventability of Meningococcal Clone, Greater Aachen Region, Germany
Johannes Elias
, Leo M. Schouls, Ingrid van de Pol, Wendy C. Keijzers, Diana R. Martin, Anne Glennie, Philipp Oster, Matthias Frosch, Ulrich Vogel1, and Arie van der Ende1
, Leo M. Schouls, Ingrid van de Pol, Wendy C. Keijzers, Diana R. Martin, Anne Glennie, Philipp Oster, Matthias Frosch, Ulrich Vogel1, and Arie van der Ende1Table 1
Positively and negatively correlating MLVA-MLST pairs, Neisseria meningitis clone, Greater Aachen Region, Germany, 2001–2006*
| Association | MT | ST | N | NEXP | N (MT] | N (ST] | J | JEXP | p value |
|---|---|---|---|---|---|---|---|---|---|
| Positive |
19 | 42 | 91 | 38 | 209 | 209 | 0.2783 | 0.1013 | 0 |
| 30 | 40 | 19 | 3 | 38 | 82 | 0.1881 | 0.0235 | 0 | |
| 78 | 1374 | 25 | 2 | 54 | 39 | 0.3676 | 0.0199 | 0 | |
| 27 |
40 |
18 |
4 |
59 |
82 |
0.1452 |
0.032 |
0.00002 |
|
| Negative | 27 | 41 | 3 | 16 | 60 | 292 | 0.0086 | 0.0462 | 0 |
| 30 | 42 | 1 | 7 | 38 | 209 | 0.0041 | 0.0287 | 0 | |
| 78 | 41 | 4 | 14 | 54 | 292 | 0.0117 | 0.0416 | 0.00004 |
*MLVA, multilocus variable tandem repeat analysis; MLST, multilocus sequent type; MT, MLVA type; ST, multi-locus-sequence type, N, no. strains with MT and ST; NEXP, expected number of strains with MT and ST; N (MT], no.strains with MT; N (ST], no. strains with ST; J, Jaccard index; JEXP, expected Jaccard index; p, 2-tailed p values (see text).
