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Volume 16, Number 4—April 2010
CME ACTIVITY - Research

Community-associated Methicillin-Resistant Staphylococcus aureus Strains in Pediatric Intensive Care Unit1

Aaron M. MilstoneComments to Author , Karen C. Carroll, Tracy Ross, K. Alexander Shangraw, and Trish M. Perl
Author affiliations: The Johns Hopkins University School of Medicine, Baltimore, Maryland, USA

Main Article

Table 2

Characteristics of patients with and without MRSA colonization at the time of PICU admission, The Johns Hopkins University Hospital, Baltimore, MD, USA, March 2007–May 2008*

CharacteristicGroup 1,† n = 72Group 2,‡ n = 1,117Group 3, n = 24§p value
Group 2 vs. group 1Group 3 vs. group 1
Demographic
Median age, y (IQR)3 (0–7.5)5 (1–12)10.5 (3–13)0.02<0.01
Male sex38 (53)616 (55)13 (54)0.690.91
Race
White28 (39)640 (57)10 (42)Referent¶Referent¶
African American39 (54)352 (32)13 (54)<0.0010.89
Other
5 (7)
126 (11)
1 (4)
0.86
0.62
Clinical
Known MRSA carrier#18 (25)0 (0)24 (100)
Hospitalization in previous 12 mo
42 (58)
308 (28)
14 (58)
<0.001
0.41
Outcomes
PICU length of stay,** median (IQR)3 (1–7)2 (1–4)2.5 (1–9)<0.0010.96
Hospital length of stay,** median (IQR)8 (3.5–15.5)5 (3–10)6 (3/5–14.5)<0.010.70

*MRSA, methicillin-resistant Staphylococcus aureus; PICU, pediatric intensive care unit; IQR, interquartile range. Values reported as no. (%) unless otherwise specified.
†MRSA colonized: patients who had MRSA grow in an admission nasal surveillance culture or in any clinical culture within 3 days of PICU admission.
‡Not MRSA colonized/no institutional history of MRSA colonization.
§Not MRSA colonized/institutional history of MRSA colonization.
¶Obtained from univariate logistic regression analysis.
#Patients with institutional history of MRSA colonization or infection.
**Data were log transformed before regression analysis to account for skewing.

Main Article

1These data were presented in part at the Annual Scientific Meeting of the Society of Healthcare Epidemiology of America, Orlando, Florida, USA, April 2008.

Page created: December 23, 2010
Page updated: December 23, 2010
Page reviewed: December 23, 2010
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