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Volume 16, Number 4—April 2010

CME ACTIVITY

Community-associated Methicillin-Resistant Staphylococcus aureus Strains in Pediatric Intensive Care Unit1

Aaron M. MilstoneComments to Author , Karen C. Carroll, Tracy Ross, K. Alexander Shangraw, and Trish M. Perl
Author affiliations: The Johns Hopkins University School of Medicine, Baltimore, Maryland, USA

Main Article

Table 3

Characteristics of patients colonized with different MRSA strain types at the time of PICU admission, The Johns Hopkins Hospital, Baltimore, MD, USA, March 2007–May 2008*

CharacteristicPatients colonized with 
CA-MRSA strain, n = 40Patients colonized with 
HA-MRSA strain, n = 26OR (95% CI)†
Demographic
Median age, y (IQR)3.8 (1.0–5.9)4.0 (1.0–9.5)0.98 (0.90–1.07)
Male sex22 (55)14 (54)1.05 (0.39–2.82)
Race
White15 (35)9 (38)Referent
African American23 (58)13 (50)1.1 (0.36–3.10)
Other
2 (5)
4 (15)
0.3 (0.05–1.98)
Clinical
Newly identified MRSA carrier32 (80)20 (77)1.2 (0.36–3.97)
Hospitalized in previous 12 mo20 (50)19 (73)0.37 (0.13–1.07)
ICU admission in previous 12 mo13 (33)26 (62)0.31 (0.11–0.84)
Length of stay in hospital before 
 PICU admission, median (range)
0 (0–28)
0 (0–14)
1.02 (0.92–1.15)
Primary service
Medical24 (60)12 (46)Referent
Surgical16 (40)14 (54)0.57 (0.21–1.55)
Admitted to PICU from inpatient unit
6 (19)
5 (15)
0.74 (0.20–2.73)
Outcomes
PICU length of stay,‡ median (IQR)3 (1–7.5)3 (2–7)1.05 (0.79–1.40)
Hospital length of stay,‡ median (IQR)8 (4.5–28.5)8.5 (3–15)1.04 (0.97–2.04)

*MRSA, methicillin-resistant Staphylococcus aureus; PICU, pediatric intensive care unit; CA-MRSA, community-associated MRSA; HA-MRSA, hospital-associated MRSA; OR, odds ratio; CI, confidence interval; IQR, interquartile range. Values reported as no. (%) unless otherwise specified.
†Obtained from univariate logistic regression analysis.
‡Data were log transformed before regression analysis to account for skewing.

Main Article

1These data were presented in part at the Annual Scientific Meeting of the Society of Healthcare Epidemiology of America, Orlando, Florida, USA, April 2008.

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