Volume 16, Number 4—April 2010
CME ACTIVITY
Community-associated Methicillin-Resistant Staphylococcus aureus Strains in Pediatric Intensive Care Unit1
, Karen C. Carroll, Tracy Ross, K. Alexander Shangraw, and Trish M. PerlTable 2
Characteristics of patients with and without MRSA colonization at the time of PICU admission, The Johns Hopkins University Hospital, Baltimore, MD, USA, March 2007–May 2008*
| Characteristic | Group 1,† n = 72 | Group 2,‡ n = 1,117 | Group 3, n = 24§ | p value | |
|---|---|---|---|---|---|
| Group 2 vs. group 1 | Group 3 vs. group 1 | ||||
| Demographic | |||||
| Median age, y (IQR) | 3 (0–7.5) | 5 (1–12) | 10.5 (3–13) | 0.02 | <0.01 |
| Male sex | 38 (53) | 616 (55) | 13 (54) | 0.69 | 0.91 |
| Race | |||||
| White | 28 (39) | 640 (57) | 10 (42) | Referent¶ | Referent¶ |
| African American | 39 (54) | 352 (32) | 13 (54) | <0.001 | 0.89 |
| Other | 5 (7) | 126 (11) | 1 (4) | 0.86 | 0.62 |
| Clinical | |||||
| Known MRSA carrier# | 18 (25) | 0 (0) | 24 (100) | ||
| Hospitalization in previous 12 mo | 42 (58) | 308 (28) | 14 (58) | <0.001 | 0.41 |
| Outcomes | |||||
| PICU length of stay,** median (IQR) | 3 (1–7) | 2 (1–4) | 2.5 (1–9) | <0.001 | 0.96 |
| Hospital length of stay,** median (IQR) | 8 (3.5–15.5) | 5 (3–10) | 6 (3/5–14.5) | <0.01 | 0.70 |
*MRSA, methicillin-resistant Staphylococcus aureus; PICU, pediatric intensive care unit; IQR, interquartile range. Values reported as no. (%) unless otherwise specified.
†MRSA colonized: patients who had MRSA grow in an admission nasal surveillance culture or in any clinical culture within 3 days of PICU admission.
‡Not MRSA colonized/no institutional history of MRSA colonization.
§Not MRSA colonized/institutional history of MRSA colonization.
¶Obtained from univariate logistic regression analysis.
#Patients with institutional history of MRSA colonization or infection.
**Data were log transformed before regression analysis to account for skewing.
