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Volume 16, Number 5—May 2010

Dispatch

Vitamin D Deficiency and Tuberculosis Progression

Najeeha Talat, Sharon Perry, Julie Parsonnet, Ghaffar Dawood, and Rabia HussainComments to Author 
Author affiliations: Aga Khan University, Karachi, Pakistan (N. Talat, R. Hussain); Stanford University School of Medicine, Stanford, California, USA (S. Perry, J. Parsonnet); Masoomeen General Hospital, Karachi, Pakistan (G. Dawood)

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Table

Prevalence of vitamin D deficiency in a cohort study of household contacts of tuberculosis patients, Karachi, Pakistan*

Baseline characteristic Total, no. (%) Deficient, no. (%) Insufficient, no. (%) Sufficient, no. (%) p value
Age group, y
6–17 44 (34) 38 (86) 4 (9) 2 (5) 0.13
>18
84 (66)
63 (75)
14 (17)
7 (8)

Sex
Male 54 (42) 35 (65) 12 (22) 7 (13) 0.003
Female
74 (58)
66 (89)
6 (8)
2 (3)

Tuberculin skin test
>10 mm 101 (79) 81 (80) 14 (14) 6 (6) 0.49
<10 mm
27 (21)
20 (74)
4 (15)
3 (11)

Total 128 (100)† 101 (79) 18 (14) 9 (7)

*Deficient, <20 ng/mL; insufficient, 20–30 ng/mL; sufficient, >30 ng/mL. p values derived by χ2 test for comparison of deficient and insufficient or sufficient levels.
†Excluding 1 person with indeterminate result.

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