Emerging Infectious Disease ISSN: 1080-6059

High Diversity and Ancient Common Ancestry of Lymphocytic Choriomeningitis Virus

Cesar G. Albariño¹

, Gustavo Palacios¹, Marina L. Khristova, Bobbie R. Erickson, Serena A. Carroll, James A. Comer, Jeffrey Hui, Thomas Briese, Kirsten St. George, Thomas G. Ksiazek², W. Ian Lipkin, and Stuart T. Nichol

Author affiliations: Centers for Disease Control and Prevention, Atlanta, Georgia, USA (C.G. Albariño, M.L. Khristova, B.R. Erickson, S.A. Carroll, J.A. Comer, T.G. Ksiazek, S.T. Nichol); Columbia University, New York, New York, USA (G. Palacios, J. Hui, T. Briese, W.I. Lipkin); New York State Department of Health, Albany, New York, USA (K. St. George)

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Appendix Figure 1

Schematic of lymphocytic choriomeningitis virus (LCMV) Z open reading frame.
The N-terminal myristoylation site (31), RING motif, and late domains are all highly conserved among the LCMV strains analyzed. Unexpectedly, the Z protein of the H935_Georgia_1984 virus strain is 1 aa longer than all the others.

Appendix Figure 1. Schematic of lymphocytic choriomeningitis virus (LCMV) Z open reading frame. The N-terminal myristoylation site (31), RING motif, and late domains are all highly conserved among the LCMV strains analyzed. Unexpectedly, the Z protein of the H935_Georgia_1984 virus strain is 1 aa longer than all the others.

Main Article

¹These authors contributed equally to this article.

²Current affiliation: University of Texas Medical Branch, Galveston, Texas, USA.

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