High Diversity and Ancient Common Ancestry of Lymphocytic Choriomeningitis Virus
Cesar G. Albariño1 , Gustavo Palacios1, Marina L. Khristova, Bobbie R. Erickson, Serena A. Carroll, James A. Comer, Jeffrey Hui, Thomas Briese, Kirsten St. George, Thomas G. Ksiazek2, W. Ian Lipkin, and Stuart T. Nichol
Author affiliations: Centers for Disease Control and Prevention, Atlanta, Georgia, USA (C.G. Albariño, M.L. Khristova, B.R. Erickson, S.A. Carroll, J.A. Comer, T.G. Ksiazek, S.T. Nichol); Columbia University, New York, New York, USA (G. Palacios, J. Hui, T. Briese, W.I. Lipkin); New York State Department of Health, Albany, New York, USA (K. St. George)
Appendix Figure 1. Schematic of lymphocytic choriomeningitis virus (LCMV) Z open reading frame.
The N-terminal myristoylation site (31), RING motif, and late domains are all highly conserved among the LCMV strains analyzed. Unexpectedly, the Z protein of the H935_Georgia_1984 virus strain is 1 aa longer than all the others.
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