Emerging Infectious Disease ISSN: 1080-6059

Comparative Genomics of Vibrio cholerae from Haiti, Asia, and Africa

Aleisha R. Reimer, Gary Van Domselaar, Steven Stroika, Matthew Walker, Heather Kent, Cheryl Tarr, Deborah Talkington, Lori Rowe, Melissa Olsen-Rasmussen, Michael Frace, Scott Sammons, Georges Anicet Dahourou, Jacques Boncy, Anthony M. Smith, Philip Mabon, Aaron Petkau, Morag Graham, Matthew W. Gilmour, Peter Gerner-Smidt

, and the V. cholerae Outbreak Genomics Task Force

Author affiliations: Author affiliations: Public Health Agency of Canada, Winnipeg, Manitoba, Canada (A.R. Reimer, G. Van Domselaar, M. Walker, H. Kent, P. Mabon, A. Petkau, M. Graham, M.W. Gilmour); Centers for Disease Control and Prevention, Atlanta, Georgia, USA (S. Stroika, C. Tarr, D. Talkington, L. Rowe, M. Olsen-Rasmussen, M. Frace, S. Sammons, P. Gerner-Smidt); Centers for Disease Control and Prevention, Port-au-Prince, Haiti (G.A. Dahourou); Ministry of Public Health and Population, Port-au-Prince (J. Boncy); National Institute for Communicable Diseases, Johannesburg, South Africa (A.M. Smith)

Main Article

Figure 1

Whole-genome neighbor-joining tree of Vibrio cholerae isolate from cholera outbreak in Haiti, fall 2010; concurrent clinical isolates with pulsed-field gel electrophoresis pattern-matched combinations; reference isolates sequenced in this study; and available reference sequences. Sequence alignments of quality draft or complete genomes were performed by using Progressive Mauve (16) and visualized by using PhyML version 3.0 (17). Whole-genome relationship of Haiti isolates with closest genetic re

Figure 1. Whole-genome neighbor-joining tree of Vibrio cholerae isolate from cholera outbreak in Haiti, fall 2010; concurrent clinical isolates with pulsed-field gel electrophoresis pattern-matched combinations; reference isolates sequenced in this study; and available reference sequences. Sequence alignments of quality draft or complete genomes were performed by using Progressive Mauve (16) and visualized by using PhyML version 3.0 (17). Whole-genome relationship of Haiti isolates with closest genetic relatives is shown in the inset. Scale bar indicates nucleotides substitutions per site.

Main Article

¹Members of the V. cholerae Outbreak Genomics Task Force are Arunmozhi Balajee, Shanna Bolcen, Cheryl A. Bopp, John Besser, Ifeoma Ezeoke, Patricia Fields, Molly Freeman, Lori Gladney, Dhwani Govil, Michael S. Humphrys, Maria Sjölund-Karlsson, Karen H. Keddy, Elizabeth Neuhaus, Michele M. Parsons, Efrain Ribot, Maryann Turnsek, Shaun Tyler, Jean M. Whichard, Anne Whitney, and the authors.

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