Emerging Infectious Disease ISSN: 1080-6059

- Add this to...
- Favorites
- Del.icio.us
- Digg
- Facebook
- Google Bookmarks
- Yahoo MyWeb

Comparative Genomics of Vibrio cholerae from Haiti, Asia, and Africa

Aleisha R. Reimer, Gary Van Domselaar, Steven Stroika, Matthew Walker, Heather Kent, Cheryl Tarr, Deborah Talkington, Lori Rowe, Melissa Olsen-Rasmussen, Michael Frace, Scott Sammons, Georges Anicet Dahourou, Jacques Boncy, Anthony M. Smith, Philip Mabon, Aaron Petkau, Morag Graham, Matthew W. Gilmour, Peter Gerner-Smidt

, and the V. cholerae Outbreak Genomics Task Force

Author affiliations: Author affiliations: Public Health Agency of Canada, Winnipeg, Manitoba, Canada (A.R. Reimer, G. Van Domselaar, M. Walker, H. Kent, P. Mabon, A. Petkau, M. Graham, M.W. Gilmour); Centers for Disease Control and Prevention, Atlanta, Georgia, USA (S. Stroika, C. Tarr, D. Talkington, L. Rowe, M. Olsen-Rasmussen, M. Frace, S. Sammons, P. Gerner-Smidt); Centers for Disease Control and Prevention, Port-au-Prince, Haiti (G.A. Dahourou); Ministry of Public Health and Population, Port-au-Prince (J. Boncy); National Institute for Communicable Diseases, Johannesburg, South Africa (A.M. Smith)

Main Article

Table 1

Characteristics of Vibrio cholerae isolates from Haiti, Asia, Africa, and the United States*

Isolate	Serotype	ctxB allele†	PFGE patterns		Date of collection	Origin of infection	Comment or GenBank accession no. (reference)
Isolate	Serotype	ctxB allele†	SfiI	NotI	Date of collection	Origin of infection	Comment or GenBank accession no. (reference)
2010EL-1961	Ogawa	B-7	KZGS12.0088	KZGN11.0092	2010 Oct 17	Haiti	Earliest Haiti outbreak case
2010EL-1786	Ogawa	B-7	KZGS12.0088	KZGN11.0092	2010	Artibonite, Haiti	None
2010EL-1792	Ogawa	B-7	KZGS12.0088	KZGN11.0092	2010	Artibonite, Haiti	None
2010EL-1798	Ogawa	B-7	KZGS12.0088	KZGN11.0092	2010	Haiti	None
2010EL-2010N	Ogawa	B-7	KZGS12.0160	KZGN11.0134	2010	Haiti	Nonhemolytic
2010EL-2010H	Ogawa	B-7	KZGS12.0088	KZGN11.0092	2010	Haiti	Hemolytic
2011EL-1089	Ogawa	B-7	KZGS12.0088	KZGN11.0092	2010 Nov 27	South Department, Haiti	None
2011EL-1133	Ogawa	B-7	KZGS12.0088	KZGN11.0092	2011 Jan 26	Northwest Department, Haiti	Travel associated
2011V-1021	Ogawa	B-7	KZGS12.0088	KZGN11.0092	2011	Dominican Republic	Travel associated
2009V-1085	Ogawa	B-7	KZGS12.0088	KZGN11.0092	2009	Sri Lanka/India	Travel associated
2009V-1096	Inaba	B-7	KZGS12.0088	KZGN11.0092	2009	India	Travel associated
2010EL-1749	Ogawa	B-7	KZGS12.0088	KZGN11.0092	2010	Cameroon	Outbreak
2009V-1131	Ogawa	B-7	KZGS12.0088	KZGN11.0092	2009	India	Travel associated
3554–08	Ogawa	B-7	KZGS12.0088	KZGN11.0092	2008	Nepal	Travel associated
2011EL-1137	Ogawa	B-1	KZGS12.0089	KZGN11.0092	2009	South Africa	Outbreak
2009V-1046	Ogawa	B-1	KZGS12.0088	KZGN11.0092	2009	Pakistan	Travel associated
2009V-1116	Ogawa	B-1	KZGS12.0088	KZGN11.0092	2009	Pakistan	Travel associated
2010V-1014	Ogawa	B-1	KZGS12.0088	KZGN11.0092	2010	Pakistan	Travel associated
3582–05	Inaba	B-1	KZGS12.0088	KZGN11.0092	2005	Pakistan	Travel associated
3500–05	Inaba	B-1	KZGS12.0088	KZGN11.0092	2005	India	Travel associated
3546–06	Inaba	B-1	KZGS12.0088	KZGN11.0092	2006	India	Travel associated
3569–08	Inaba	B-1	KZGS12.0055	KZGN11.0029	2008	US Gulf Coast	Environmental isolate
C6706	Inaba	B-3	KZGS12.0114	KZGN11.0033	1991	Peru	Latin America outbreak
CIRS101‡	Inaba	B-1	Unknown	Unknown	2002	Dhaka, Bangladesh	NZ_ACVW00000000 (4)
MJ-1236‡	Inaba	B-1	Unknown	Unknown	1994	Matlab, Bangladesh	NC_012667, NC_012668 (4)
O395‡	Ogawa	B-1	Unknown	Unknown	1965	India	NC_009456, NC_009457 (1)
N16961‡	Inaba	B-3	Unknown	Unknown	1970s	Bangladesh	NC_002505, NC_002506 (13)
M66–2‡	Unknown	§	Unknown	Unknown	1937	Makassar, Indonesia	NC_012578, NC_012580 (1)

*ctxB, cholera toxin subunit B; PFGE, pulsed-field gel electrophoresis.
†B-7, classical allele, Orissa variant; B-1, classical allele; B-3, El Tor allele (2)
‡These isolates have been sequenced by other investigators, and sequences have been deposited in GenBank. PFGE was not performed on these isolates.
§This isolate does not contain ctxB.

Main Article

¹Members of the V. cholerae Outbreak Genomics Task Force are Arunmozhi Balajee, Shanna Bolcen, Cheryl A. Bopp, John Besser, Ifeoma Ezeoke, Patricia Fields, Molly Freeman, Lori Gladney, Dhwani Govil, Michael S. Humphrys, Maria Sjölund-Karlsson, Karen H. Keddy, Elizabeth Neuhaus, Michele M. Parsons, Efrain Ribot, Maryann Turnsek, Shaun Tyler, Jean M. Whichard, Anne Whitney, and the authors.

Top of Page