Volume 17, Number 12—December 2011
Letter
Humans as Source of Mycobacterium tuberculosis Infection in Cattle, Spain
Beatriz Romero, Sabrina Rodríguez, Javier Bezos, Rosa Díaz, M. Francisca Copano, Isabel Merediz, Olga Mínguez, Sergio Marqués, Juan J. Palacios, Darío García de Viedma, José Luis Sáez, Ana Mateos, Alicia Aranaz, Lucas Domínguez, and Lucía de Juan
Table
Relevant information about Mycobacterium tuberculosis infection in 3 cattle farms in Spain*
| Variable | Farm 1 | Farm 2 | Farm 3 |
|---|---|---|---|
| Cattle herd | |||
| No. animals | 6 | 54 | >200 |
| Production | Beef | Beef | Dairy |
| Previous status | TB free | TB-free | Non–TB free |
| No. reactors |
1 |
31 |
12 |
| M. tuberculosis infection in cattle | |||
| Year of isolation | 2007 | 2008 | 2009 |
| Age, mo | 9 | 4 | 3 |
| IDTB/interferon-γ | Pos/not determined | Neg/neg | Pos/not determined |
| TB-compatible lesion | No | No | No |
| Spoligotyping profile | SIT2537 | SIT1564 | SIT58 |
| MIRU-VNTR profile† | 253533233433236252211423 | 3′52334232455457251213423 | 254343243232325262213423 |
| Co-infection with
other mycobacteria |
Yes
(M. avium subsp. hominissuis)‡ |
Yes
(M. bovis) |
No |
| M. tuberculosis infection in human | |||
| Active tuberculosis | Yes | Yes | Yes |
| Spoligotyping profile | SIT2537 | Not available | SIT58 |
| MIRU-VNTR profile† | 253533233433236252211423 | 3′52334232455457251213423 | 254343243232325262213423 |
| Origin | Spain | Eastern Europe | Spain |
*TB, tuberculosis; IDTB, intradermal tuberculin tested according to the European Council Directive 64/432/EEC; pos, positive; neg, negative; MIRU-VNTR, mycobacterial interspersed repetitive unit–variable number tandem repeat.
†MIRU-VNTR profile on the basis of the 24 MIRU-VNTR loci (7).
‡Co-infection in the same animal.
